电化学脱羧磺化：一种温和有效的获取有机硫酸盐的方法

IF 3.6 2区化学 Q1 CHEMISTRY, ORGANIC

Journal of Organic Chemistry Pub Date : 2025-06-04 DOI:10.1021/acs.joc.5c00504

Wei Sheng, Huanhuan Peng, Chunlan Song, Jiakun Li

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引用次数: 0

摘要

硫酸化是病理和生理过程中至关重要的转化过程。然而，传统的有机硫酸盐合成主要依赖于o -磺化，这仅限于含羟基的底物。在此，我们开发了一种实用且经济高效的电化学脱羧磺化方法。这种方法开辟了从现成的羧酸中获得有机硫酸盐的新途径，具有广泛的底物范围和良好的官能团相容性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Electrochemical Decarboxylative Sulfation: A Mild and Efficient Method to Access Organosulfates

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Electrochemical Decarboxylative Sulfation: A Mild and Efficient Method to Access Organosulfates

Sulfation is a crucial transformation in both pathological and physiological processes. However, the conventional synthesis of organosulfates primarily relies on O-sulfonation, which is limited to hydroxyl-containing substrates. Here, we developed a practical and cost-efficient method for electrochemical decarboxylative sulfation. This approach opens new avenues to access organosulfates from readily available carboxylic acids with a broad substrate scope and good functional group compatibility.

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来源期刊

Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.