急性脑卒中住院后抗抑郁药物使用的相关因素

IF 1.3 4区 医学 Q4 PSYCHIATRY
Hely D Nanavati, Nicole C Wright, Melissa J Smith, Shakia T Hardy, Virginia J Howard, Chen Lin
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引用次数: 0

摘要

目的抑郁是卒中后最常见的心理健康并发症,导致卒中后预后不良。很少有观察性研究报道与这些患者使用抗抑郁药相关的因素。因此,本研究评估了急性脑卒中住院后出院时接受抗抑郁药处方的患者和临床特征。方法选取机构卒中登记(2019年10月1日至2020年10月31日)中入院的急性卒中或短暂性脑缺血发作患者。使用电子健康记录审查来评估出院时的抗抑郁药处方和预测因素,如人口统计学、健康行为、临床合并症和中风预后特征。结果803例脑卒中患者中,220例(27.4%)在出院时服用抗抑郁药物,其中82例(12.8%)在出院时开始服用抗抑郁药物。多变量模型显示性别(女性vs男性OR = 1.53;95% CI = 1.09, 2.16),种族(黑人vs白人:OR = 0.67;95% CI = 0.47, 0.96),临床合并症数量(OR = 1.16;95% CI = 1.03, 1.32),抑郁史(OR = 4.91;95% CI = 2.59, 9.31)和出院处置(住院康复设施vs家庭:OR = 1.52;95% CI = 1.01, 2.30)与服用抗抑郁药处方显著相关。出院处置(到住院康复机构)是唯一与出院时开始服用抗抑郁药处方相关的变量(OR = 2.92;95% ci = 1.62, 5.28)。结论脑卒中后患者抗抑郁药处方在女性、白人成年人和住院康复机构出院患者中更为常见。这些研究结果描述了抗抑郁药的处方模式,强调了中风后抗抑郁药使用的具体指南的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Factors associated with antidepressant use following hospitalization for acute stroke.

ObjectiveDepression is the most common mental health complication after stroke, leading to poor post-stroke outcomes. Few observational studies have reported factors associated with antidepressant use in these patients. Therefore, this study assessed patient and clinical characteristics associated with receiving antidepressant prescriptions at discharge following hospital admission for acute stroke.MethodsIdentified were patients admitted with acute stroke or transient ischemic attack from the institutional stroke registry (October 1, 2019, through October 31, 2020). Electronic health record review was used to assess antidepressant prescription at discharge and predictors such as demographics, health behaviors, clinical comorbidities, and stroke prognostic characteristics.ResultsOut of 803 patients with stroke, 220 (27.4%) received an antidepressant prescription at discharge, including 82 (12.8%) patients who were started on antidepressants at discharge. A multivariable model indicated that sex (female vs male OR = 1.53; 95% CI = 1.09, 2.16), race (Black vs White: OR = 0.67; 95% CI = 0.47, 0.96), number of clinical comorbidities (OR = 1.16; 95% CI = 1.03, 1.32), history of depression (OR = 4.91; 95% CI = 2.59, 9.31), and discharge disposition (to inpatient rehabilitation facility vs home: OR = 1.52; 95% CI = 1.01, 2.30) were significantly associated with receipt of antidepressant prescriptions among all users. Discharge disposition (to an inpatient rehabilitation facility) was the only variable associated with initiating an antidepressant prescription at discharge (OR = 2.92; 95% CI = 1.62, 5.28).ConclusionAntidepressant prescriptions for poststroke patients were more frequent among females, White adults, and those discharged to an inpatient rehabilitation facility. These findings describing antidepressant prescription patterns underscore the need for specific guidelines aiding antidepressant use after stroke.

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来源期刊
CiteScore
3.00
自引率
5.00%
发文量
55
审稿时长
6-12 weeks
期刊介绍: The International Journal of Psychiatry in Medicine (IJPM) bridges the gap between clinical psychiatry research and primary care clinical research. Providing a forum for addressing: The relevance of psychobiological, psychological, social, familial, religious, and cultural factors in the development and treatment of illness; the relationship of biomarkers to psychiatric symptoms and syndromes in primary care...
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