血管性认知障碍患者的治疗特点

Q3 Medicine
G N Belskaya
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引用次数: 0

摘要

血管性认知障碍(Vascular cognitive impairment, CI)因其高发性、进行性、致残性等特点,是一个亟待解决的医学问题。CI可能不仅与中风的直接影响有关,还与血管性和神经退行性的发病前认知能力下降有关。除了血管危险因素外,还有许多导致痴呆的因素,并且注意到CI性质的异质性。由于大多数CI患者的合并症以及对医疗建议的依从性较低,因此CI患者的管理很复杂。该综述致力于考虑综合治疗的可能性,包括非药物、医学治疗方法,以及影响血管性痴呆可改变危险因素的生活方式改变。数据显示,在CI患者(包括慢性脑缺血引起的患者)的复杂治疗中,使用延长形式的己酮茶碱(Vasonit),日剂量为600- 1200mg,在疗效和安全性方面,以及提高患者依从性方面的方便性。为了说明,根据我们自己使用Vasonite的经验给出了一个临床例子。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Treatment features of patients with vascular cognitive impairments].

Vascular cognitive impairment (CI) is an urgent medical problem due to its high prevalence, progressive course, and high degree of disability. CI may be associated not only with the direct effects of stroke, but also with the presence of premorbid cognitive decline of both vascular and neurodegenerative nature. In addition to vascular risk factors, there are a number of factors leading to dementia, and the heterogeneity of the nature of CI is noted. The management of patients with CI is complicated due to the comorbidity of most of them, as well as low adherence to medical recommendations. The review is devoted to the consideration of the possibility of complex therapy, including non-drug, medical treatment methods, as well as lifestyle changes that affect modifiable risk factors for vascular dementia. Data are presented on the expediency of using a prolonged form of pentoxifylline (Vasonit) in a daily dosage of 600-1200 mg in the complex treatment of patients with CI (including those caused by chronic cerebral ischemia) in terms of efficacy and safety, as well as improving patient compliance. To illustrate, a clinical example is given based on our own experience using Vasonite.

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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
287
审稿时长
3-6 weeks
期刊介绍: Одно из старейших медицинских изданий России, основанное в 1901 году. Создание журнала связано с именами выдающихся деятелей отечественной медицины, вошедших в историю мировой психиатрии и неврологии, – С.С. Корсакова и А.Я. Кожевникова. Широкий диапазон предлагаемых журналом материалов и разнообразие форм их представления привлекают внимание научных работников и врачей, опытных и начинающих медиков, причем не только неврологов и психиатров, но и специалистов смежных областей медицины.
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