冠状动脉内夹层/血肿的介入治疗:综合综述。

IF 3.1 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Federico Giannino, Gabriele Carciotto, Francesco Pallante, Gabriele Monciino, Matteo Mancuso, Davide Raspanti, Giustina Iuvara, Manuela Ajello, Stefania Lo Giudice, Marcello Marchetta, Samuel La Cola, Maurizio Cusmà Piccione, Vittorio Virga, Antonio Micari, Giampiero Vizzari
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引用次数: 0

摘要

回顾目的:冠状动脉内剥离和血肿是急性冠状动脉综合征(ACS)罕见但重要的病因,常导致心肌缺血和梗死。鉴于其不同的临床表现和最佳管理策略的证据有限,本综述旨在评估目前的治疗方法,包括保守,经皮和手术选择,同时强调新兴的创新和未来的研究方向。最近的发现:最近的研究强调了先进的冠状动脉内成像技术,如光学相干断层扫描(OCT)和血管内超声(IVUS),在提高诊断准确性和指导治疗决策方面的作用。保守治疗越来越被认为是稳定患者的可行选择,可以提供良好的长期预后。经皮冠状动脉介入治疗(PCI)适用于持续缺血、血流动力学不稳定或高危解剖特征的病例,尽管它存在夹层扩散和冠状动脉破裂等风险。在PCI失败或左主干受累的情况下,手术干预仍然是必不可少的,尽管存在手术挑战,但仍显示出较高的生存率。根据患者特异性因素和冠状动脉内成像,量身定制的治疗策略对于优化冠状动脉内夹层和血肿的预后至关重要。虽然保守治疗在某些情况下是有效的,但PCI和手术干预对高危患者仍然至关重要。未来的研究应侧重于完善风险分层工具,改进成像方式,制定标准化的治疗算法,以提高患者护理和临床结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Interventional Management of Intracoronary Dissection/Hematoma: A Comprehensive Review.

Purpose of review: Intracoronary dissection and hematoma are rare but significant causes of acute coronary syndromes (ACS), often leading to myocardial ischemia and infarction. Given their heterogeneous clinical presentation and the limited evidence on optimal management strategies, this review aims to evaluate current treatment approaches, including conservative, percutaneous, and surgical options, while highlighting emerging innovations and future research directions.

Recent findings: Recent studies emphasize the role of advanced intracoronary imaging techniques, such as optical coherence tomography (OCT) and intravascular ultrasound (IVUS), in improving diagnostic accuracy and guiding therapeutic decisions. Conservative management is increasingly recognized as a viable option for stable patients, offering favorable long-term outcomes. Percutaneous coronary intervention (PCI) is indicated in cases with ongoing ischemia, hemodynamic instability, or high-risk anatomical features, though it carries risks such as dissection propagation and coronary rupture. Surgical intervention remains essential in cases of failed PCI or left main stem involvement, demonstrating high survival rates despite procedural challenges. Tailored therapeutic strategies, informed by patient-specific factors and intracoronary imaging, are crucial for optimizing outcomes in intracoronary dissection and hematoma. While conservative management is effective in selected cases, PCI and surgical interventions remain vital for high-risk patients. Future research should focus on refining risk stratification tools, improving imaging modalities, and developing standardized treatment algorithms to enhance patient care and clinical outcomes.

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来源期刊
Current Cardiology Reports
Current Cardiology Reports CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
6.20
自引率
2.70%
发文量
209
期刊介绍: The aim of this journal is to provide timely perspectives from experts on current advances in cardiovascular medicine. We also seek to provide reviews that highlight the most important recently published papers selected from the wealth of available cardiovascular literature. We accomplish this aim by appointing key authorities in major subject areas across the discipline. Section editors select topics to be reviewed by leading experts who emphasize recent developments and highlight important papers published over the past year. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.
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