ws03.02高强度间歇训练和中等强度连续训练在提高囊性纤维化成人次最大强度运动能力方面是相同的

IF 5.4 2区医学 Q1 RESPIRATORY SYSTEM

Journal of Cystic Fibrosis Pub Date : 2025-06-01 DOI:10.1016/j.jcf.2025.03.505

W. Gruber , J. Koop , F.A. Haegele , C. Falkenberg , S. Dewey , B. Weiser , A. Bosy-Westphal

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引用次数: 0

摘要

目的：本随机对照试验探讨高强度间歇训练（HIIT）和中强度连续训练（MICT）对囊性纤维化（pwCF）成年患者亚最大运动强度运动能力的影响。方法60例成年pwCF患者（34f/26m，平均年龄38.9±10.4岁，19 ~ 58岁，ppFEV1 67.9±19.3,35.0 ~ 110.0%）同意参与研究。使用循环几何法测定呼吸阈值2 （VT2）时的摄氧量（VO2）和工作量(W)。参与者被随机分配到HIIT组或MICT组，根据肺部疾病严重程度（ppFEV1 35-70%或>；70%）进行匹配。两组每周锻炼5次，包括3次循环体能计训练。HIIT组在90% VO2peak下进行10次，每次1分钟，然后在40% VO2peak下进行2分钟的主动恢复，每次30分钟（10分钟高强度，20分钟主动恢复），而MICT组在60% VO2peak的恒定负荷下完成30分钟。数据是在两家CF专业机构为期4周的住院康复计划中收集的。结果两组vo2vt2和WVT2 （HIIT: VO2peak, D +9.4%, Wpeak +10.3%, MICT: VO2peak, D +14.0%, Wpeak +15.1%）均显著升高（p<0.001）。MICT组有稍大的变化，但时间x训练交互显示无显著结果（p>0.05）。结论在为期4周的康复过程中，hiit和MICT对改善成年pwCF患者的运动能力同样有效。训练方式的选择应该是个性化的，考虑到诸如可用时间、初始运动能力、个人兴趣、偏好和享受等方面。由于这项研究代表了短期的运动干预，未来的研究应该在更长的时间内调查这些训练方式的相对有效性。

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WS03.02High-intensity interval training and moderate-intensity continuous training are equivalent in improving exercise capacity at submaximal intensity in adults with cystic fibrosis

Objectives

This randomised controlled trial investigates the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on exercise capacity at submaximal exercise intensity in adult people with Cystic Fibrosis (pwCF).

Methods

60 adult pwCF (34f/26m, mean age 38.9±10.4yrs, 19-58years, ppFEV₁ 67.9±19.3, 35.0-110.0%) agreed to participate. Cycle-ergometry was used to determine Oxygen Uptake (VO2) and Workload (W) at Ventilatory Threshold 2 (VT2). Participants were randomly assigned to either the HIIT or MICT group, with matching based on lung disease severity (ppFEV1 35-70% or >70%). Both groups exercised 5 times per week, including three cycle ergometer sessions. The HIIT group performed 10 bouts of 1 minute at 90% VO2peak, followed by 2 minutes of active recovery at 40% VO2peak for a total of 30 minutes per session (10 minutes high-intensity, 20 minutes active recovery), while the MICT group completed 30 minutes at a constant load of 60% VO2peak. Data were collected during a 4-week inpatient rehabilitation program at two specialized CF institutions.

Results

VO2_VT2 and W_VT2 increased significantly (p<0.001) in both groups (HIIT: VO2peak, D +9.4%, Wpeak +10.3%, MICT: VO2peak, D +14.0%, Wpeak +15.1%). The MICT group had slightly greater changes, but the time x training interaction revealed non-significant results (p>0.05). No adverse events were reported, and the dropout rate was similar between groups

Conclusion

HIIT and MICT were equally effective in improving exercise capacity in adult pwCF during this 4-week rehabilitation course. The choice of training modalitiy should be individualized, considering aspects such as available time, initial exercise capacity, individual interests, preferences, and enjoyment. As this study represents a short-term exercise intervention, future studies should investigate the comparative effectiveness of these training modalities over longer time periods.

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来源期刊

Journal of Cystic Fibrosis 医学-呼吸系统

CiteScore

10.10

自引率

13.50%

发文量

1361

审稿时长

50 days

期刊介绍： The Journal of Cystic Fibrosis is the official journal of the European Cystic Fibrosis Society. The journal is devoted to promoting the research and treatment of cystic fibrosis. To this end the journal publishes original scientific articles, editorials, case reports, short communications and other information relevant to cystic fibrosis. The journal also publishes news and articles concerning the activities and policies of the ECFS as well as those of other societies related the ECFS.