ws02.05睡眠对囊性纤维化患儿生活质量的影响

IF 5.4 2区医学 Q1 RESPIRATORY SYSTEM

Journal of Cystic Fibrosis Pub Date : 2025-06-01 DOI:10.1016/j.jcf.2025.03.502

F.F. Karkın Gürel , D. Ademhan Tural , H. Yetisgin , S.S. Akyan Soydas , S. Ozkan Tabakci , S. Eryilmaz Polat , G.D. Tugcu , G. Cinel

{"title":"ws02.05睡眠对囊性纤维化患儿生活质量的影响","authors":"F.F. Karkın Gürel , D. Ademhan Tural , H. Yetisgin , S.S. Akyan Soydas , S. Ozkan Tabakci , S. Eryilmaz Polat , G.D. Tugcu , G. Cinel","doi":"10.1016/j.jcf.2025.03.502","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>We aimed to evaluate the effects of sleep-disordered breathing, sleep quality, and sleepiness on the quality of life (QoL) of children with cystic fibrosis (cwCF).</div></div><div><h3>Method</h3><div>This cross-sectional observational study was conducted on cwCF and healthy children (control) aged 6-18 from July to November 2024. Aged-appropriate QoL, Pediatric Sleep Questionnaire (PSQ), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale for Children and Adolescents (ESS-CHAD) were applied to all participants. Demographics of all participants and clinical characteristics of cwCF were collected. Subgroup analyses were made between patients who used (n:17) modulators and those who did not (n:23).</div></div><div><h3>Results</h3><div>The study included 40 cwCF and 54 controls. There were no differences according to age and sex distribution between the groups. The QoL results are summarized in Table 1. PSQ, PSQI, and EUS scores were statistically significantly higher in cwCF than in the controls (p-values, respectively; <0.001, <0.001, 0.013). Table 2 summarizes the regression analysis results of sleep-disordered breathing, sleep quality, and sleepiness on QoL in cwCF aged 6-13. A statistically significant difference was found in the digestive subscale of QoL between patients receiving and not receiving modulators in cwCF aged 6-13 (p=0.036). The frequency of sleep-disordered breathing (p=0.047), poor sleep quality (p=0.030), and daytime sleepiness (p=0.248) was more common in patients who did not use modulators than those who did</div></div><div><h3>Conclusion</h3><div>Sleep-disordered breathing, daytime sleepiness, and sleep quality were found to have important roles in the quality of life of cwCF.</div></div>","PeriodicalId":15452,"journal":{"name":"Journal of Cystic Fibrosis","volume":"24 ","pages":"Pages S4-S5"},"PeriodicalIF":5.4000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"WS02.05The effect of sleep on the quality of life of children with cystic fibrosis\",\"authors\":\"F.F. Karkın Gürel , D. Ademhan Tural , H. Yetisgin , S.S. Akyan Soydas , S. Ozkan Tabakci , S. Eryilmaz Polat , G.D. Tugcu , G. Cinel\",\"doi\":\"10.1016/j.jcf.2025.03.502\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><div>We aimed to evaluate the effects of sleep-disordered breathing, sleep quality, and sleepiness on the quality of life (QoL) of children with cystic fibrosis (cwCF).</div></div><div><h3>Method</h3><div>This cross-sectional observational study was conducted on cwCF and healthy children (control) aged 6-18 from July to November 2024. Aged-appropriate QoL, Pediatric Sleep Questionnaire (PSQ), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale for Children and Adolescents (ESS-CHAD) were applied to all participants. Demographics of all participants and clinical characteristics of cwCF were collected. Subgroup analyses were made between patients who used (n:17) modulators and those who did not (n:23).</div></div><div><h3>Results</h3><div>The study included 40 cwCF and 54 controls. There were no differences according to age and sex distribution between the groups. The QoL results are summarized in Table 1. PSQ, PSQI, and EUS scores were statistically significantly higher in cwCF than in the controls (p-values, respectively; <0.001, <0.001, 0.013). Table 2 summarizes the regression analysis results of sleep-disordered breathing, sleep quality, and sleepiness on QoL in cwCF aged 6-13. A statistically significant difference was found in the digestive subscale of QoL between patients receiving and not receiving modulators in cwCF aged 6-13 (p=0.036). The frequency of sleep-disordered breathing (p=0.047), poor sleep quality (p=0.030), and daytime sleepiness (p=0.248) was more common in patients who did not use modulators than those who did</div></div><div><h3>Conclusion</h3><div>Sleep-disordered breathing, daytime sleepiness, and sleep quality were found to have important roles in the quality of life of cwCF.</div></div>\",\"PeriodicalId\":15452,\"journal\":{\"name\":\"Journal of Cystic Fibrosis\",\"volume\":\"24 \",\"pages\":\"Pages S4-S5\"},\"PeriodicalIF\":5.4000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Cystic Fibrosis\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1569199325005983\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Cystic Fibrosis","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1569199325005983","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}

引用次数: 0

摘要

目的探讨睡眠呼吸障碍、睡眠质量和嗜睡对囊性纤维化（cwCF）患儿生活质量（QoL）的影响。方法于2024年7月至11月对6-18岁的cwCF儿童和健康儿童（对照）进行横断面观察研究。采用适龄生活质量量表（QoL）、儿童睡眠问卷（PSQ）、匹兹堡睡眠质量指数（PSQI）和Epworth儿童青少年嗜睡量表（ESS-CHAD）。收集所有参与者的人口统计资料和cwCF的临床特征。在使用（n:17）调节剂和未使用（n:23）调节剂的患者之间进行亚组分析。结果本研究纳入cwCF患者40例，对照组54例。各组之间的年龄和性别分布没有差异。QoL结果总结在表1中。cwCF组PSQ、PSQI和EUS评分均显著高于对照组(p值分别为；<0.001, <0.001, 0.013)。表2总结了6-13岁cwCF中睡眠呼吸障碍、睡眠质量、嗜睡对QoL的回归分析结果。6-13岁cwCF患者接受与未接受调节剂治疗的患者的生活质量消化亚量表差异有统计学意义（p=0.036）。未使用调制剂的患者出现睡眠呼吸障碍（p=0.047）、睡眠质量差（p=0.030）和白天嗜睡（p=0.248）的频率高于使用调制剂的患者。结论睡眠呼吸障碍、白天嗜睡和睡眠质量对cwCF患者的生活质量有重要影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

WS02.05The effect of sleep on the quality of life of children with cystic fibrosis

Objectives

We aimed to evaluate the effects of sleep-disordered breathing, sleep quality, and sleepiness on the quality of life (QoL) of children with cystic fibrosis (cwCF).

Method

This cross-sectional observational study was conducted on cwCF and healthy children (control) aged 6-18 from July to November 2024. Aged-appropriate QoL, Pediatric Sleep Questionnaire (PSQ), Pittsburgh Sleep Quality Index (PSQI), and Epworth Sleepiness Scale for Children and Adolescents (ESS-CHAD) were applied to all participants. Demographics of all participants and clinical characteristics of cwCF were collected. Subgroup analyses were made between patients who used (n:17) modulators and those who did not (n:23).

Results

The study included 40 cwCF and 54 controls. There were no differences according to age and sex distribution between the groups. The QoL results are summarized in Table 1. PSQ, PSQI, and EUS scores were statistically significantly higher in cwCF than in the controls (p-values, respectively; <0.001, <0.001, 0.013). Table 2 summarizes the regression analysis results of sleep-disordered breathing, sleep quality, and sleepiness on QoL in cwCF aged 6-13. A statistically significant difference was found in the digestive subscale of QoL between patients receiving and not receiving modulators in cwCF aged 6-13 (p=0.036). The frequency of sleep-disordered breathing (p=0.047), poor sleep quality (p=0.030), and daytime sleepiness (p=0.248) was more common in patients who did not use modulators than those who did

Conclusion

Sleep-disordered breathing, daytime sleepiness, and sleep quality were found to have important roles in the quality of life of cwCF.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Cystic Fibrosis 医学-呼吸系统

CiteScore

10.10

自引率

13.50%

发文量

1361

审稿时长

50 days

期刊介绍： The Journal of Cystic Fibrosis is the official journal of the European Cystic Fibrosis Society. The journal is devoted to promoting the research and treatment of cystic fibrosis. To this end the journal publishes original scientific articles, editorials, case reports, short communications and other information relevant to cystic fibrosis. The journal also publishes news and articles concerning the activities and policies of the ECFS as well as those of other societies related the ECFS.