抗生素洗脱水泥初次全膝关节置换术治疗合并鸟分枝杆菌的膝关节脓毒性关节炎

IF 2.1 Q3 ORTHOPEDICS

Arthroplasty Today Pub Date : 2025-06-01 DOI:10.1016/j.artd.2025.101719

Andrew M. Schwartz MD , David G. Deckey MD , Danielle S. Chun MD , Thorsten M. Seyler MD, PhD , Tyler S. Watters MD

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引用次数: 0

摘要

由鸟分枝杆菌复合体（MAC）引起的膝脓毒性关节炎极为罕见。弥散性MAC感染常伴有免疫抑制状态；然而，它们也可能发生在免疫功能正常的患者身上。我们描述了一例MAC感染在原生膝关节在免疫能力的病人导致骨性破坏和继发性关节炎的改变。感染和破坏性关节病变均成功地通过单一手术治疗，包括根治性清创，初级全膝关节置换术和高剂量病原体特异性抗生素治疗，以及随后的全身抗生素治疗。手术后3年半，患者停止抗生素治疗，并继续进行功能良好的全膝关节置换术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Native Knee Septic Arthritis With Mycobacterium Avium Complex Treated With Primary Total Knee Arthroplasty With Antibiotic-Eluting Cement

Native knee septic arthritis due to Mycobacterium avium complex (MAC) is extremely rare. Disseminated MAC infections are often associated with an immunosuppressed state; however, they can occur in immunocompetent patients. We describe a case of MAC infection in the native knee in an immunocompetent patient resulting in osseous destruction and secondary arthritic changes. Both the infection and destructive arthropathy were successfully treated with a single procedure consisting of radical debridement, primary total knee arthroplasty with high-dose pathogen-specific antibiotic therapy, and subsequent systemic antibiotic therapy. At 3.5 years since surgery, the patient is off antibiotic therapy and continues to have a well-functioning total knee arthroplasty.

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来源期刊

Arthroplasty Today Medicine-Surgery

CiteScore

2.90

自引率

0.00%

发文量

258

审稿时长

40 weeks

期刊介绍： Arthroplasty Today is a companion journal to the Journal of Arthroplasty. The journal Arthroplasty Today brings together the clinical and scientific foundations for joint replacement of the hip and knee in an open-access, online format. Arthroplasty Today solicits manuscripts of the highest quality from all areas of scientific endeavor that relate to joint replacement or the treatment of its complications, including those dealing with patient outcomes, economic and policy issues, prosthetic design, biomechanics, biomaterials, and biologic response to arthroplasty. The journal focuses on case reports. It is the purpose of Arthroplasty Today to present material to practicing orthopaedic surgeons that will keep them abreast of developments in the field, prove useful in the care of patients, and aid in understanding the scientific foundation of this subspecialty area of joint replacement. The international members of the Editorial Board provide a worldwide perspective for the journal''s area of interest. Their participation ensures that each issue of Arthroplasty Today provides the reader with timely, peer-reviewed articles of the highest quality.