单克隆抗体治疗多囊卵巢综合征？

IF 27.7 1区生物学 Q1 CELL BIOLOGY

Cell metabolism Pub Date : 2025-06-03 DOI:10.1016/j.cmet.2025.05.002

David H. Abbott, Daniel A. Dumesic

引用次数: 0

摘要

目前还没有治愈多囊卵巢综合征（PCOS）的方法，只能治疗其高度流行的生殖、心脏代谢和心理症状。多囊卵巢综合征的早期症状出现在婴儿期。这使得Cotellessa等人能够在雌性小鼠模型的婴儿期开发和实施中和抗体疗法，以根除多囊卵巢综合征的症状。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Monoclonal antibody therapy for PCOS?

There is no cure for polycystic ovary syndrome (PCOS), only treatment for its highly prevalent reproductive, cardiometabolic, and psychological symptoms. Early signs of PCOS appear during infancy. This enabled Cotellessa et al.¹ to develop and administer neutralizing antibody therapy during infancy in a female mouse model to eradicate PCOS symptomology.

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来源期刊

Cell metabolism 生物-内分泌学与代谢

CiteScore

48.60

自引率

1.40%

发文量

173

审稿时长

2.5 months

期刊介绍： Cell Metabolism is a top research journal established in 2005 that focuses on publishing original and impactful papers in the field of metabolic research.It covers a wide range of topics including diabetes, obesity, cardiovascular biology, aging and stress responses, circadian biology, and many others. Cell Metabolism aims to contribute to the advancement of metabolic research by providing a platform for the publication and dissemination of high-quality research and thought-provoking articles.