The Impact of Model-based Deep-learning Reconstruction Compared with that of Compressed Sensing-Sensitivity Encoding on the Image Quality and Precision of Cine Cardiac MR in Evaluating Left-ventricular Volume and Strain: A Study on Healthy Volunteers.

Purpose: To evaluate the effect of model-based deep-learning reconstruction (DLR) compared with that of compressed sensing-sensitivity encoding (CS) on cine cardiac magnetic resonance (CMR).

Methods: Cine CMR images of 10 healthy volunteers were obtained with reduction factors of 2, 4, 6, and 8 and reconstructed using CS and DLR. The visual image quality scores assessed sharpness, image noise, and artifacts. Left-ventricular (LV) end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) were manually measured. LV global circumferential strain (GCS) was automatically measured using the software. The precision of EDV, ESV, SV, EF, and GCS measurements was compared between CS and DLR using Bland-Altman analysis with full-sampling data as the gold standard.

Results: Compared with CS, DLR significantly improved image quality with reduction factors of 6 and 8. The precision of EDV and ESV with a reduction factor of 8, and GCS with reduction factors of 6 and 8 measurements improved with DLR compared with CS, whereas those of SV and EF measurements were not different between DLR and CS.

Conclusion: The effect of DLR on cine CMR's image quality and precision in evaluating quantitative volume and strain was equal or superior to that of CS. DLR may replace CS for cine CMR.