Michelle J Bovin, Kristina Caudle, Frank W Weathers, Michael Hollifield, Paula P Schnurr, Brian P Marx
{"title":"《精神疾病诊断与统计手册》第五版（CAPS-5）中临床应用PTSD量表的集中评估中心的开发与评估。","authors":"Michelle J Bovin, Kristina Caudle, Frank W Weathers, Michael Hollifield, Paula P Schnurr, Brian P Marx","doi":"10.1037/tra0001949","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>In clinical trials for posttraumatic stress disorder (PTSD), reliable and valid assessment is essential. However, accuracy can be compromised due to site-level variation, assessor unmasking, and participant burden associated with multiple visits to a study site. We therefore created a centralized assessment hub in which raters were trained to administer the Clinician-Administered PTSD Scale for <i>Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition</i> (Weathers et al., 2013) remotely via telephone.</p><p><strong>Method: </strong>We developed a systematic training protocol for Veteran Affairs (VA) Cooperative Study 591, the largest multisite PTSD psychotherapy trial ever conducted (<i>N</i> = 916, Schnurr et al., 2022). We trained 15 raters, ranging from trainees to licensed clinical psychologists. Our protocol included three steps: (1) didactics, (2) scoring calibration, and (3) mock interviews. Step 3 was repeated until raters achieved 85% reliability with an expert. Randomly selected interviews (<i>n</i> = 200) were used to calculate interrater reliability.</p><p><strong>Results: </strong>Reliability was outstanding for both PTSD diagnosis (κ = .90) and total severity score (intraclass correlation = .98). Assessment time period did not impact PTSD diagnostic agreement (<i>χ</i>² = 5.60; <i>p</i> = .23) but did affect total symptom severity (<i>F</i> = 4.43; <i>p</i> = .002). In contrast, rater educational attainment impacted diagnostic (<i>χ</i>² = 5.00; <i>p</i> = .025) but not total severity score (<i>t</i> = .85; <i>p</i> = .39) agreement.</p><p><strong>Conclusions: </strong>Our Clinician-Administered PTSD Scale for <i>Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition</i> training protocol was used successfully in the largest PTSD clinical trial to date. The use of a centralized assessment hub ensured highly accurate assessment that likely could not have been achieved using site-based raters across multiple sites. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>","PeriodicalId":20982,"journal":{"name":"Psychological trauma : theory, research, practice and policy","volume":" ","pages":""},"PeriodicalIF":2.7000,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Development and evaluation of a centralized assessment hub for the clinician-administered PTSD Scale for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (CAPS-5).\",\"authors\":\"Michelle J Bovin, Kristina Caudle, Frank W Weathers, Michael Hollifield, Paula P Schnurr, Brian P Marx\",\"doi\":\"10.1037/tra0001949\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>In clinical trials for posttraumatic stress disorder (PTSD), reliable and valid assessment is essential. However, accuracy can be compromised due to site-level variation, assessor unmasking, and participant burden associated with multiple visits to a study site. We therefore created a centralized assessment hub in which raters were trained to administer the Clinician-Administered PTSD Scale for <i>Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition</i> (Weathers et al., 2013) remotely via telephone.</p><p><strong>Method: </strong>We developed a systematic training protocol for Veteran Affairs (VA) Cooperative Study 591, the largest multisite PTSD psychotherapy trial ever conducted (<i>N</i> = 916, Schnurr et al., 2022). We trained 15 raters, ranging from trainees to licensed clinical psychologists. Our protocol included three steps: (1) didactics, (2) scoring calibration, and (3) mock interviews. Step 3 was repeated until raters achieved 85% reliability with an expert. Randomly selected interviews (<i>n</i> = 200) were used to calculate interrater reliability.</p><p><strong>Results: </strong>Reliability was outstanding for both PTSD diagnosis (κ = .90) and total severity score (intraclass correlation = .98). Assessment time period did not impact PTSD diagnostic agreement (<i>χ</i>² = 5.60; <i>p</i> = .23) but did affect total symptom severity (<i>F</i> = 4.43; <i>p</i> = .002). In contrast, rater educational attainment impacted diagnostic (<i>χ</i>² = 5.00; <i>p</i> = .025) but not total severity score (<i>t</i> = .85; <i>p</i> = .39) agreement.</p><p><strong>Conclusions: </strong>Our Clinician-Administered PTSD Scale for <i>Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition</i> training protocol was used successfully in the largest PTSD clinical trial to date. The use of a centralized assessment hub ensured highly accurate assessment that likely could not have been achieved using site-based raters across multiple sites. (PsycInfo Database Record (c) 2025 APA, all rights reserved).</p>\",\"PeriodicalId\":20982,\"journal\":{\"name\":\"Psychological trauma : theory, research, practice and policy\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2025-06-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Psychological trauma : theory, research, practice and policy\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://doi.org/10.1037/tra0001949\",\"RegionNum\":2,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Psychological trauma : theory, research, practice and policy","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1037/tra0001949","RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}
Development and evaluation of a centralized assessment hub for the clinician-administered PTSD Scale for the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (CAPS-5).
Objective: In clinical trials for posttraumatic stress disorder (PTSD), reliable and valid assessment is essential. However, accuracy can be compromised due to site-level variation, assessor unmasking, and participant burden associated with multiple visits to a study site. We therefore created a centralized assessment hub in which raters were trained to administer the Clinician-Administered PTSD Scale for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (Weathers et al., 2013) remotely via telephone.
Method: We developed a systematic training protocol for Veteran Affairs (VA) Cooperative Study 591, the largest multisite PTSD psychotherapy trial ever conducted (N = 916, Schnurr et al., 2022). We trained 15 raters, ranging from trainees to licensed clinical psychologists. Our protocol included three steps: (1) didactics, (2) scoring calibration, and (3) mock interviews. Step 3 was repeated until raters achieved 85% reliability with an expert. Randomly selected interviews (n = 200) were used to calculate interrater reliability.
Results: Reliability was outstanding for both PTSD diagnosis (κ = .90) and total severity score (intraclass correlation = .98). Assessment time period did not impact PTSD diagnostic agreement (χ² = 5.60; p = .23) but did affect total symptom severity (F = 4.43; p = .002). In contrast, rater educational attainment impacted diagnostic (χ² = 5.00; p = .025) but not total severity score (t = .85; p = .39) agreement.
Conclusions: Our Clinician-Administered PTSD Scale for Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition training protocol was used successfully in the largest PTSD clinical trial to date. The use of a centralized assessment hub ensured highly accurate assessment that likely could not have been achieved using site-based raters across multiple sites. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
期刊介绍：
Psychological Trauma: Theory, Research, Practice, and Policy publishes empirical research on the psychological effects of trauma. The journal is intended to be a forum for an interdisciplinary discussion on trauma, blending science, theory, practice, and policy.
The journal publishes empirical research on a wide range of trauma-related topics, including:
-Psychological treatments and effects
-Promotion of education about effects of and treatment for trauma
-Assessment and diagnosis of trauma
-Pathophysiology of trauma reactions
-Health services (delivery of services to trauma populations)
-Epidemiological studies and risk factor studies
-Neuroimaging studies
-Trauma and cultural competence
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