Raphael Enrique Tiongco, Miljun Catacata, Pia Vanessa Basilio, Eliezer John Castro, Benjie Clemente, Raenard Emmanuel Dayrit, Michelle Charina Gomez, Michael John Dominguez, Shamar Lo Lasta, Jefferyl Kae Pandac, Maria Ruth Pineda-Cortel
{"title":"一项最新荟萃分析发现，非O型血与妊娠糖尿病发展的可能性增加有关。","authors":"Raphael Enrique Tiongco, Miljun Catacata, Pia Vanessa Basilio, Eliezer John Castro, Benjie Clemente, Raenard Emmanuel Dayrit, Michelle Charina Gomez, Michael John Dominguez, Shamar Lo Lasta, Jefferyl Kae Pandac, Maria Ruth Pineda-Cortel","doi":"10.1007/s40200-025-01653-1","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Several factors are attributed to the development of gestational diabetes mellitus (GDM), but its association with the ABO blood group is still unexplored. Hence, we performed a meta-analysis to examine this association.</p><p><strong>Methods: </strong>Relevant articles were obtained from various databases until April 5, 2025. All related data were extracted by two authors and summarized in a customized spreadsheet. Odds ratios (ORs) and 95% confidence intervals (CIs) were computed and interpreted.</p><p><strong>Results: </strong>The pooled analysis showed homogeneity in the outcomes. Pooled ORs show that pregnant women with non-blood type O showed more significant associations than those with blood type O.</p><p><strong>Conclusion: </strong>Overall, the present meta-analysis suggests that individuals with non-blood type O have an increased risk of developing GDM compared to those with blood type O. However, further studies stratifying populations based on insulin resistance, gut microbiota, and inflammation in association with ABO and GDM development are needed to confirm these claims.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s40200-025-01653-1.</p>","PeriodicalId":15635,"journal":{"name":"Journal of Diabetes and Metabolic Disorders","volume":"24 1","pages":"133"},"PeriodicalIF":1.6000,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12125415/pdf/","citationCount":"0","resultStr":"{\"title\":\"Non-blood type O is associated with an increased likelihood of gestational diabetes development: findings from an updated meta-analysis.\",\"authors\":\"Raphael Enrique Tiongco, Miljun Catacata, Pia Vanessa Basilio, Eliezer John Castro, Benjie Clemente, Raenard Emmanuel Dayrit, Michelle Charina Gomez, Michael John Dominguez, Shamar Lo Lasta, Jefferyl Kae Pandac, Maria Ruth Pineda-Cortel\",\"doi\":\"10.1007/s40200-025-01653-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Several factors are attributed to the development of gestational diabetes mellitus (GDM), but its association with the ABO blood group is still unexplored. 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However, further studies stratifying populations based on insulin resistance, gut microbiota, and inflammation in association with ABO and GDM development are needed to confirm these claims.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s40200-025-01653-1.</p>\",\"PeriodicalId\":15635,\"journal\":{\"name\":\"Journal of Diabetes and Metabolic Disorders\",\"volume\":\"24 1\",\"pages\":\"133\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-05-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12125415/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Diabetes and Metabolic Disorders\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s40200-025-01653-1\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/6/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Diabetes and Metabolic Disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s40200-025-01653-1","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Non-blood type O is associated with an increased likelihood of gestational diabetes development: findings from an updated meta-analysis.
Purpose: Several factors are attributed to the development of gestational diabetes mellitus (GDM), but its association with the ABO blood group is still unexplored. Hence, we performed a meta-analysis to examine this association.
Methods: Relevant articles were obtained from various databases until April 5, 2025. All related data were extracted by two authors and summarized in a customized spreadsheet. Odds ratios (ORs) and 95% confidence intervals (CIs) were computed and interpreted.
Results: The pooled analysis showed homogeneity in the outcomes. Pooled ORs show that pregnant women with non-blood type O showed more significant associations than those with blood type O.
Conclusion: Overall, the present meta-analysis suggests that individuals with non-blood type O have an increased risk of developing GDM compared to those with blood type O. However, further studies stratifying populations based on insulin resistance, gut microbiota, and inflammation in association with ABO and GDM development are needed to confirm these claims.
Supplementary information: The online version contains supplementary material available at 10.1007/s40200-025-01653-1.
期刊介绍：
Journal of Diabetes & Metabolic Disorders is a peer reviewed journal which publishes original clinical and translational articles and reviews in the field of endocrinology and provides a forum of debate of the highest quality on these issues. Topics of interest include, but are not limited to, diabetes, lipid disorders, metabolic disorders, osteoporosis, interdisciplinary practices in endocrinology, cardiovascular and metabolic risk, aging research, obesity, traditional medicine, pychosomatic research, behavioral medicine, ethics and evidence-based practices.As of Jan 2018 the journal is published by Springer as a hybrid journal with no article processing charges. All articles published before 2018 are available free of charge on springerlink.Unofficial 2017 2-year Impact Factor: 1.816.
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