刚果民主共和国东部高血压患者的生活质量和药物依从性：一项横断面研究

IF 1.7 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2025-06-02 DOI:10.1016/j.cegh.2025.102083

Roland Muyisa , Emile Watumwa , Divine Mataula , Arma Nzanzu , Amani Ngavo , Robert Kanduki , Apollinaire SaaSita , Jacques Wahangire , Jean Paul Mwalitsa , Adélar Kalima , François Mbahweka

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引用次数: 0

摘要

高血压是一个重大的公共卫生问题，是世界上最普遍的慢性疾病之一，影响着发达国家和发展中国家。值得注意的是，刚果民主共和国有关高血压的数据仍然很少。本研究旨在评估抗高血压药物依从性对高血压患者生活质量的影响。方法以2024年7月1日至11月1日在Katwa、Butembo和Musienene地区18岁及以上的高血压患者为研究对象，采用方便抽样法抽取211例患者。纳入需要至少6个月的治疗。使用SF-36量表测量健康相关生活质量（HRQoL），使用MMAS-8量表评估药物依从性。通过描述性统计和线性回归分析数据，检验依从性与生活质量之间的关系。结果调查结果显示，参与者的不依从率为56.40%。此外，生活质量各方面的平均得分相对较低，特别是在一般健康领域，得分为36.11%，表明生活质量较差。高水平的药物依从性与特定生活质量领域的改善之间存在显著的相关性，包括身体功能、社会功能、身体限制和心理健康。结论高血压患者治疗依从性低，与生活质量评分差相关，而高依从性与更好的生活质量改善相关。

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Quality of life and medication adherence of hypertensive patients in Eastern DR Congo: a cross-sectional study

Introduction

Hypertension represents a significant public health issue and stands as one of the most prevalent chronic diseases worldwide, affecting both developed and developing nations. Notably, data regarding hypertension in the Democratic Republic of the Congo (DRC) remains scarce. This study sought to evaluate the effects of adherence to antihypertensive medication on the quality of life among hypertensive patients.

Method

This study focused on hypertensive patients aged 18 and older in Katwa, Butembo, and Musienene from July 1 to November 1, 2024, involving 211 patients selected by convenience sampling. Inclusion required at least six months of treatment. Health-Related Quality of Life (HRQoL) was measured using the SF-36 scale, and medication adherence was assessed with the MMAS-8. Data were analyzed through descriptive statistics and linear regression to examine the relationship between adherence and quality of life.

Results

The findings indicated a non-adherence rate of 56.40 % among participants. Furthermore, the mean scores across various dimensions of quality of life were observed to be relatively low, particularly in the domain of general health, which registered a score of 36.11 %, indicative of poor quality of life. A significant correlation was identified between high levels of adherence to medication and improvement in specific domains of quality of life, including physical function, social function, physical limitation, and mental health.

Conclusion

Hypertensive patients had low treatment adherence, correlating with poor quality-of-life scores, while high adherence was linked to better quality-of-life improvements.

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.