苦参总生物碱外用液对绵羊蜱虫的防治效果

IF 2.2 2区农林科学 Q2 PARASITOLOGY

Veterinary parasitology Pub Date : 2025-05-28 DOI:10.1016/j.vetpar.2025.110469

Chuan Yu , Kexu Jin , Kaige Li , Zhihui Hao

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引用次数: 0

摘要

皮炎可能是由寄生在皮肤上的寄生虫引起的。为了评价苦豆总生物碱溶液的临床杀螨活性，对羊体内寄生虫进行了采集、拍照和初步鉴定，并用石蜡切片对寄生虫进行了蜱类组织学检查。选择患蜱羊，设计3个剂量的水稀释溶液，评价其外用倒液治疗的临床效果，并与对照用药二吡酯溶液进行比较。结果表明，其杀虫活性明显。临床疗效与对照用药不同剂量的吡甲酯溶液外用相当。绵羊感染后瘙痒、脱毛、轮流啃咬等主要临床症状得到缓解。给药前后血常规检查及血液生化指标均未受影响。结果提示，32.5 mg/kg和65 mg/kg外用溶液可有效控制蜱虫的孳生。在治疗过程中没有毒性的证据。

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Clinical effectiveness of total alkaloids of Sophora alopecuroides L. topical solution administrated pour on against ticks in sheep

The dermatitis could be caused by parasites infested in skin. The aim of this study was to evaluate the clinical acaricidal activity of a total alkaloid solution from Sophora alopecuroides L. The parasites in sheep were collected, photographed and initially identified, then the histology of parasites were examined through paraffin sections as ticks species. The tick-infested sheep were selected and three dosages of the solution diluted in water were designed to evaluate the clinical effectiveness in topical solution pour on to compare with the control medication of Dimpylate solution. The results demonstrated that the insecticidal activity were obvious. The clinical effectiveness were comparable to the control medication of Dimpylate solution in different dosages in topical administration. The primary clinical symptoms of pruitus, hair removal, gnawed in turn back in sheep infestations were alleviated. The blood routine examinations and blood biochemical indicators were not influenced before administration and after observation. These results suggest that the topical solution in 32.5 mg/kg and 65 mg/kg can effectively control ticks infestation effectively in clinical. There was no evidence of toxicity during the treatment.

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来源期刊

Veterinary parasitology 农林科学-寄生虫学

CiteScore

5.30

自引率

7.70%

发文量

126

审稿时长

36 days

期刊介绍： The journal Veterinary Parasitology has an open access mirror journal,Veterinary Parasitology: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. This journal is concerned with those aspects of helminthology, protozoology and entomology which are of interest to animal health investigators, veterinary practitioners and others with a special interest in parasitology. Papers of the highest quality dealing with all aspects of disease prevention, pathology, treatment, epidemiology, and control of parasites in all domesticated animals, fall within the scope of the journal. Papers of geographically limited (local) interest which are not of interest to an international audience will not be accepted. Authors who submit papers based on local data will need to indicate why their paper is relevant to a broader readership. Parasitological studies on laboratory animals fall within the scope of the journal only if they provide a reasonably close model of a disease of domestic animals. Additionally the journal will consider papers relating to wildlife species where they may act as disease reservoirs to domestic animals, or as a zoonotic reservoir. Case studies considered to be unique or of specific interest to the journal, will also be considered on occasions at the Editors'' discretion. Papers dealing exclusively with the taxonomy of parasites do not fall within the scope of the journal.