Seungyeon Lee, Nang Kyeong Lee, Seung Won Lee, Yong Joon Kim
{"title":"新冠肺炎大流行前后全国普通人群贝尔氏麻痹发病率的变化:一项生态学研究","authors":"Seungyeon Lee, Nang Kyeong Lee, Seung Won Lee, Yong Joon Kim","doi":"10.1002/jmv.70431","DOIUrl":null,"url":null,"abstract":"<p>This nationwide population-based ecological study investigated changes in the incidence of Bell's palsy (BP) in South Korea during the COVID-19 pandemic. Patients diagnosed with BP between January 2017 and December 2022 were analyzed. Considering the unique progression of the COVID-19 pandemic and corresponding public health responses in South Korea, the study period was divided into four phases: pre-COVID-19 (2017–2019), non-pharmaceutical intervention (NPI, 2020), nationwide vaccination (2021), and nationwide infection (2022). Poisson regression was used to calculate incidence rate ratios (IRRs) for each pandemic phase compared to the pre-COVID-19 baseline, adjusting for age and sex. Among 103 482 patients, BP incidence significantly decreased during the vaccination (IRR 0.96; 95% CI, 0.94–0.98) and infection (IRR 0.95; 95% CI, 0.93–0.97) phases (<i>p</i> < 0.001). These trends were more pronounced among women and older adults and did not correlate with national vaccination or infection rates. Our findings suggest that the incidence of BP did not increase during the COVID-19 era at the level of the general population nationwide. Further studies using individual-level data on COVID-19 infection and vaccination are needed to clarify their potential direct impact on BP incidence.</p>","PeriodicalId":16354,"journal":{"name":"Journal of Medical Virology","volume":"97 6","pages":""},"PeriodicalIF":6.8000,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmv.70431","citationCount":"0","resultStr":"{\"title\":\"Changes in the Nationwide Incidence of Bell's Palsy in the General Population Before and After the COVID-19 Pandemic: An Ecological Study\",\"authors\":\"Seungyeon Lee, Nang Kyeong Lee, Seung Won Lee, Yong Joon Kim\",\"doi\":\"10.1002/jmv.70431\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>This nationwide population-based ecological study investigated changes in the incidence of Bell's palsy (BP) in South Korea during the COVID-19 pandemic. Patients diagnosed with BP between January 2017 and December 2022 were analyzed. Considering the unique progression of the COVID-19 pandemic and corresponding public health responses in South Korea, the study period was divided into four phases: pre-COVID-19 (2017–2019), non-pharmaceutical intervention (NPI, 2020), nationwide vaccination (2021), and nationwide infection (2022). Poisson regression was used to calculate incidence rate ratios (IRRs) for each pandemic phase compared to the pre-COVID-19 baseline, adjusting for age and sex. Among 103 482 patients, BP incidence significantly decreased during the vaccination (IRR 0.96; 95% CI, 0.94–0.98) and infection (IRR 0.95; 95% CI, 0.93–0.97) phases (<i>p</i> < 0.001). These trends were more pronounced among women and older adults and did not correlate with national vaccination or infection rates. Our findings suggest that the incidence of BP did not increase during the COVID-19 era at the level of the general population nationwide. Further studies using individual-level data on COVID-19 infection and vaccination are needed to clarify their potential direct impact on BP incidence.</p>\",\"PeriodicalId\":16354,\"journal\":{\"name\":\"Journal of Medical Virology\",\"volume\":\"97 6\",\"pages\":\"\"},\"PeriodicalIF\":6.8000,\"publicationDate\":\"2025-06-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jmv.70431\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical Virology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/jmv.70431\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"VIROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Virology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jmv.70431","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"VIROLOGY","Score":null,"Total":0}
Changes in the Nationwide Incidence of Bell's Palsy in the General Population Before and After the COVID-19 Pandemic: An Ecological Study
This nationwide population-based ecological study investigated changes in the incidence of Bell's palsy (BP) in South Korea during the COVID-19 pandemic. Patients diagnosed with BP between January 2017 and December 2022 were analyzed. Considering the unique progression of the COVID-19 pandemic and corresponding public health responses in South Korea, the study period was divided into four phases: pre-COVID-19 (2017–2019), non-pharmaceutical intervention (NPI, 2020), nationwide vaccination (2021), and nationwide infection (2022). Poisson regression was used to calculate incidence rate ratios (IRRs) for each pandemic phase compared to the pre-COVID-19 baseline, adjusting for age and sex. Among 103 482 patients, BP incidence significantly decreased during the vaccination (IRR 0.96; 95% CI, 0.94–0.98) and infection (IRR 0.95; 95% CI, 0.93–0.97) phases (p < 0.001). These trends were more pronounced among women and older adults and did not correlate with national vaccination or infection rates. Our findings suggest that the incidence of BP did not increase during the COVID-19 era at the level of the general population nationwide. Further studies using individual-level data on COVID-19 infection and vaccination are needed to clarify their potential direct impact on BP incidence.
期刊介绍:
The Journal of Medical Virology focuses on publishing original scientific papers on both basic and applied research related to viruses that affect humans. The journal publishes reports covering a wide range of topics, including the characterization, diagnosis, epidemiology, immunology, and pathogenesis of human virus infections. It also includes studies on virus morphology, genetics, replication, and interactions with host cells.
The intended readership of the journal includes virologists, microbiologists, immunologists, infectious disease specialists, diagnostic laboratory technologists, epidemiologists, hematologists, and cell biologists.
The Journal of Medical Virology is indexed and abstracted in various databases, including Abstracts in Anthropology (Sage), CABI, AgBiotech News & Information, National Agricultural Library, Biological Abstracts, Embase, Global Health, Web of Science, Veterinary Bulletin, and others.