Computational and statistical analysis of wall shear stress role in assessing rupture risk of ICA saccular aneurysms

In this article, comprehensive assessing rupture risk in intracranial internal carotid artery (ICA) saccular aneurysms are done by computational and statistical approaches. Hemodynamic study of 36 saccular aneurysms (ruptured and unruptured) were done via computational fluid dynamics and consequently, these hemodynamic features are analyzed via statistical methods to find important connections between rupture risk and these obtained hemodynamic parameters. In this work, the range of significant factors of wall shear stress (WSS) and pressure is fully compared. The potential connections between these factors and aneurysm rupture are evaluated by Weibull statistical model. The spatial distribution of these parameters was charted across the aneurysm sac surface to pinpoint regions with an elevated risk of rupture. Results revealed that that while Mean might not differ significantly between ruptured and unruptured groups, Max WSS tends to be 15 % higher in unruptured cases. The data of Min WSS shows that ruptured cases show a 17 % lower Min WSS. There is a greater spread in ruptured cases, with extreme high-value outliers.