Zeshan Ali Sandhu, Muhammad Asam Raza, Umme Farwa, Muhammad Saad Fareed, Abdulmajeed Alqurashi, Muhammad Latif
{"title":"碳点作为纳米载体在药物传递中的作用:目前的进展、前景和实现。","authors":"Zeshan Ali Sandhu, Muhammad Asam Raza, Umme Farwa, Muhammad Saad Fareed, Abdulmajeed Alqurashi, Muhammad Latif","doi":"10.1080/17425247.2025.2513439","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Carbon dots (CDs) are recognized as outstanding nanocarriers for drug delivery owing to their superior biocompatibility, straightforward synthetic routes, and tunable surface properties.</p><p><strong>Area covered: </strong>This review presents a comprehensive overview of recent developments in CDs within the context of drug delivery systems (DDSs) and their utilization as carriers for drug loading, stabilization, and delivery. It also describes functionalized CDs for therapeutic applications, including cancer, antimicrobial, and gene therapies. Key strategic issues such as toxicity, biodistribution, and manufacturability are thoroughly elaborated and critically evaluated to identify novel approaches to address crucial challenges.</p><p><strong>Expert opinion: </strong>The promising potential of CDs to transform current drug delivery methods is driving researchers to undertake further biological investigations regarding the application of the CDs in clinical settings, as well as to explore future prospects of CDs within the biomedical field.</p>","PeriodicalId":94004,"journal":{"name":"Expert opinion on drug delivery","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Role of carbon dots as nanocarriers in drug delivery: current advancements, prospects, and implementations.\",\"authors\":\"Zeshan Ali Sandhu, Muhammad Asam Raza, Umme Farwa, Muhammad Saad Fareed, Abdulmajeed Alqurashi, Muhammad Latif\",\"doi\":\"10.1080/17425247.2025.2513439\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Carbon dots (CDs) are recognized as outstanding nanocarriers for drug delivery owing to their superior biocompatibility, straightforward synthetic routes, and tunable surface properties.</p><p><strong>Area covered: </strong>This review presents a comprehensive overview of recent developments in CDs within the context of drug delivery systems (DDSs) and their utilization as carriers for drug loading, stabilization, and delivery. It also describes functionalized CDs for therapeutic applications, including cancer, antimicrobial, and gene therapies. Key strategic issues such as toxicity, biodistribution, and manufacturability are thoroughly elaborated and critically evaluated to identify novel approaches to address crucial challenges.</p><p><strong>Expert opinion: </strong>The promising potential of CDs to transform current drug delivery methods is driving researchers to undertake further biological investigations regarding the application of the CDs in clinical settings, as well as to explore future prospects of CDs within the biomedical field.</p>\",\"PeriodicalId\":94004,\"journal\":{\"name\":\"Expert opinion on drug delivery\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Expert opinion on drug delivery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/17425247.2025.2513439\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Expert opinion on drug delivery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/17425247.2025.2513439","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Role of carbon dots as nanocarriers in drug delivery: current advancements, prospects, and implementations.
Introduction: Carbon dots (CDs) are recognized as outstanding nanocarriers for drug delivery owing to their superior biocompatibility, straightforward synthetic routes, and tunable surface properties.
Area covered: This review presents a comprehensive overview of recent developments in CDs within the context of drug delivery systems (DDSs) and their utilization as carriers for drug loading, stabilization, and delivery. It also describes functionalized CDs for therapeutic applications, including cancer, antimicrobial, and gene therapies. Key strategic issues such as toxicity, biodistribution, and manufacturability are thoroughly elaborated and critically evaluated to identify novel approaches to address crucial challenges.
Expert opinion: The promising potential of CDs to transform current drug delivery methods is driving researchers to undertake further biological investigations regarding the application of the CDs in clinical settings, as well as to explore future prospects of CDs within the biomedical field.