Arielle Fried MD , Max Hockstein MD, MS , Anirudh Rao MD , Michael Pottash MD, MPH
{"title":"跨专业临床医生对左室辅助功能失活与透析中止的看法:一项使用小片段的横断面研究。","authors":"Arielle Fried MD , Max Hockstein MD, MS , Anirudh Rao MD , Michael Pottash MD, MPH","doi":"10.1016/j.jacadv.2025.101835","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Requests for left ventricular assist device (LVAD) deactivation may pose unique emotional and moral burdens on clinicians.</div></div><div><h3>Objectives</h3><div>The authors aimed to explore the perspectives of interprofessional clinicians regarding LVAD deactivation across clinical settings compared to cessation of hemodialysis.</div></div><div><h3>Methods</h3><div>Vignette-based interviews were conducted with a sample of interprofessional clinicians at a heart and vascular center from April 14, 2023, to June 5, 2023. Likert-scale responses to paired vignettes were analyzed descriptively and with inferential statistics.</div></div><div><h3>Results</h3><div>Eighty clinicians agreed to be interviewed for this study (27.5% physicians, 23.8% nurses, 17.5% physician trainees, 16.3% advanced practice providers, and 15% social workers, bioethicists, and chaplains). Clinicians uniformly felt that vignettes depicting LVAD deactivation were more ethically complex and less likely to be honored than dialysis discontinuation across clinical scenarios (<em>P</em> < 0.001). Clinicians were more likely to rate scenarios that described the patient without other medical comorbidities (“tired of life”) for either the patient with a LVAD or a patient on dialysis as ethically complex and were less likely to suggest honoring the patient's request (<em>P</em> < 0.001). These trends remained consistent across all demographic and clinician disciplines.</div></div><div><h3>Conclusions</h3><div>When compared to requests to discontinue hemodialysis, clinicians perceive LVAD deactivation as more ethically complex and were less likely to honor the patient's request. These differences persisted across clinical scenarios, from acutely ill to chronically ill to independent.</div></div>","PeriodicalId":73527,"journal":{"name":"JACC advances","volume":"4 6","pages":"Article 101835"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Interprofessional Clinician Perspectives on LVAD Deactivation Compared to Dialysis Discontinuation\",\"authors\":\"Arielle Fried MD , Max Hockstein MD, MS , Anirudh Rao MD , Michael Pottash MD, MPH\",\"doi\":\"10.1016/j.jacadv.2025.101835\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Requests for left ventricular assist device (LVAD) deactivation may pose unique emotional and moral burdens on clinicians.</div></div><div><h3>Objectives</h3><div>The authors aimed to explore the perspectives of interprofessional clinicians regarding LVAD deactivation across clinical settings compared to cessation of hemodialysis.</div></div><div><h3>Methods</h3><div>Vignette-based interviews were conducted with a sample of interprofessional clinicians at a heart and vascular center from April 14, 2023, to June 5, 2023. Likert-scale responses to paired vignettes were analyzed descriptively and with inferential statistics.</div></div><div><h3>Results</h3><div>Eighty clinicians agreed to be interviewed for this study (27.5% physicians, 23.8% nurses, 17.5% physician trainees, 16.3% advanced practice providers, and 15% social workers, bioethicists, and chaplains). Clinicians uniformly felt that vignettes depicting LVAD deactivation were more ethically complex and less likely to be honored than dialysis discontinuation across clinical scenarios (<em>P</em> < 0.001). Clinicians were more likely to rate scenarios that described the patient without other medical comorbidities (“tired of life”) for either the patient with a LVAD or a patient on dialysis as ethically complex and were less likely to suggest honoring the patient's request (<em>P</em> < 0.001). These trends remained consistent across all demographic and clinician disciplines.</div></div><div><h3>Conclusions</h3><div>When compared to requests to discontinue hemodialysis, clinicians perceive LVAD deactivation as more ethically complex and were less likely to honor the patient's request. These differences persisted across clinical scenarios, from acutely ill to chronically ill to independent.</div></div>\",\"PeriodicalId\":73527,\"journal\":{\"name\":\"JACC advances\",\"volume\":\"4 6\",\"pages\":\"Article 101835\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"JACC advances\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2772963X25002546\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"JACC advances","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2772963X25002546","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Interprofessional Clinician Perspectives on LVAD Deactivation Compared to Dialysis Discontinuation
Background
Requests for left ventricular assist device (LVAD) deactivation may pose unique emotional and moral burdens on clinicians.
Objectives
The authors aimed to explore the perspectives of interprofessional clinicians regarding LVAD deactivation across clinical settings compared to cessation of hemodialysis.
Methods
Vignette-based interviews were conducted with a sample of interprofessional clinicians at a heart and vascular center from April 14, 2023, to June 5, 2023. Likert-scale responses to paired vignettes were analyzed descriptively and with inferential statistics.
Results
Eighty clinicians agreed to be interviewed for this study (27.5% physicians, 23.8% nurses, 17.5% physician trainees, 16.3% advanced practice providers, and 15% social workers, bioethicists, and chaplains). Clinicians uniformly felt that vignettes depicting LVAD deactivation were more ethically complex and less likely to be honored than dialysis discontinuation across clinical scenarios (P < 0.001). Clinicians were more likely to rate scenarios that described the patient without other medical comorbidities (“tired of life”) for either the patient with a LVAD or a patient on dialysis as ethically complex and were less likely to suggest honoring the patient's request (P < 0.001). These trends remained consistent across all demographic and clinician disciplines.
Conclusions
When compared to requests to discontinue hemodialysis, clinicians perceive LVAD deactivation as more ethically complex and were less likely to honor the patient's request. These differences persisted across clinical scenarios, from acutely ill to chronically ill to independent.