{"title":"输尿管末端柔性吸引通路治疗肾结石的疗效和安全性。","authors":"Jianguo Gao, Jianer Tang, Yuefan Shen","doi":"10.12659/MSM.947055","DOIUrl":null,"url":null,"abstract":"<p><p>BACKGROUND We compared the efficacy and safety of a novel flexible-tip suctioning ureteral access sheath (NFTS-UAS) with flexible ureteroscopy (FURS) versus percutaneous nephrolithotomy (PCNL) for treating unilateral renal calculi (2-3.5 cm). MATERIAL AND METHODS This retrospective study included 337 patients (167 NFTS-UAS, 170 PCNL) treated at Huzhou Normal College's First Affiliated Hospital (March 2021-January 2024). Group 1 underwent FURS with NFTS-UAS, utilizing a flexible-tip sheath connected to a suction device for improved fragment clearance. Group 2 underwent standard PCNL. Outcomes included duration of surgery, stone-free rate (SFR), hospital stay, antibiotic use, and complications. RESULTS The NFTS-UAS group had shorter surgery times (80.02±29.44 vs 98.95±28.82 minutes; P<0.05) and hospital stays (45.62±30.59 vs 173.0±75.46 hours; P<0.05). Preoperative antibiotic use and postoperative infectious complications (eg, elevated neutrophils) were lower in the NFTS-UAS group. While NFTS-UAS had a lower day 1 SFR (68.26% vs 83.53%; P<0.05), SFRs had equalized by day 30 (85.0% vs 89.0%; P=0.21). No intraoperative complications occurred in either group. CONCLUSIONS NFTS-UAS with FURS is a viable alternative to PCNL for 2-3.5 cm renal stones, offering comparable 30-day SFRs, faster recovery, and reduced hospitalization. Further prospective studies are warranted to validate long-term outcomes.</p>","PeriodicalId":48888,"journal":{"name":"Medical Science Monitor","volume":"31 ","pages":"e947055"},"PeriodicalIF":3.1000,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Efficacy and Safety of Tip-Flexible Suctioning Ureteral Access in Renal Stone Treatment.\",\"authors\":\"Jianguo Gao, Jianer Tang, Yuefan Shen\",\"doi\":\"10.12659/MSM.947055\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>BACKGROUND We compared the efficacy and safety of a novel flexible-tip suctioning ureteral access sheath (NFTS-UAS) with flexible ureteroscopy (FURS) versus percutaneous nephrolithotomy (PCNL) for treating unilateral renal calculi (2-3.5 cm). MATERIAL AND METHODS This retrospective study included 337 patients (167 NFTS-UAS, 170 PCNL) treated at Huzhou Normal College's First Affiliated Hospital (March 2021-January 2024). Group 1 underwent FURS with NFTS-UAS, utilizing a flexible-tip sheath connected to a suction device for improved fragment clearance. Group 2 underwent standard PCNL. Outcomes included duration of surgery, stone-free rate (SFR), hospital stay, antibiotic use, and complications. RESULTS The NFTS-UAS group had shorter surgery times (80.02±29.44 vs 98.95±28.82 minutes; P<0.05) and hospital stays (45.62±30.59 vs 173.0±75.46 hours; P<0.05). Preoperative antibiotic use and postoperative infectious complications (eg, elevated neutrophils) were lower in the NFTS-UAS group. While NFTS-UAS had a lower day 1 SFR (68.26% vs 83.53%; P<0.05), SFRs had equalized by day 30 (85.0% vs 89.0%; P=0.21). No intraoperative complications occurred in either group. CONCLUSIONS NFTS-UAS with FURS is a viable alternative to PCNL for 2-3.5 cm renal stones, offering comparable 30-day SFRs, faster recovery, and reduced hospitalization. Further prospective studies are warranted to validate long-term outcomes.</p>\",\"PeriodicalId\":48888,\"journal\":{\"name\":\"Medical Science Monitor\",\"volume\":\"31 \",\"pages\":\"e947055\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2025-05-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Science Monitor\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.12659/MSM.947055\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Science Monitor","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.12659/MSM.947055","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
背景：我们比较了柔性输尿管镜（FURS）与经皮肾镜取石术（PCNL）治疗单侧（2-3.5 cm）肾结石的疗效和安全性。材料与方法本回顾性研究纳入湖州师范学院第一附属医院（2021年3月- 2024年1月）治疗的337例患者（167例NFTS-UAS， 170例PCNL）。第1组使用NFTS-UAS进行FURS，利用连接到吸力装置的柔性尖端护套来改善碎片清除。第二组行标准PCNL。结果包括手术时间、结石无结石率（SFR）、住院时间、抗生素使用和并发症。结果NFTS-UAS组手术时间短（80.02±29.44 vs 98.95±28.82）min；P
Efficacy and Safety of Tip-Flexible Suctioning Ureteral Access in Renal Stone Treatment.
BACKGROUND We compared the efficacy and safety of a novel flexible-tip suctioning ureteral access sheath (NFTS-UAS) with flexible ureteroscopy (FURS) versus percutaneous nephrolithotomy (PCNL) for treating unilateral renal calculi (2-3.5 cm). MATERIAL AND METHODS This retrospective study included 337 patients (167 NFTS-UAS, 170 PCNL) treated at Huzhou Normal College's First Affiliated Hospital (March 2021-January 2024). Group 1 underwent FURS with NFTS-UAS, utilizing a flexible-tip sheath connected to a suction device for improved fragment clearance. Group 2 underwent standard PCNL. Outcomes included duration of surgery, stone-free rate (SFR), hospital stay, antibiotic use, and complications. RESULTS The NFTS-UAS group had shorter surgery times (80.02±29.44 vs 98.95±28.82 minutes; P<0.05) and hospital stays (45.62±30.59 vs 173.0±75.46 hours; P<0.05). Preoperative antibiotic use and postoperative infectious complications (eg, elevated neutrophils) were lower in the NFTS-UAS group. While NFTS-UAS had a lower day 1 SFR (68.26% vs 83.53%; P<0.05), SFRs had equalized by day 30 (85.0% vs 89.0%; P=0.21). No intraoperative complications occurred in either group. CONCLUSIONS NFTS-UAS with FURS is a viable alternative to PCNL for 2-3.5 cm renal stones, offering comparable 30-day SFRs, faster recovery, and reduced hospitalization. Further prospective studies are warranted to validate long-term outcomes.
期刊介绍：
Medical Science Monitor (MSM) established in 1995 is an international, peer-reviewed scientific journal which publishes original articles in Clinical Medicine and related disciplines such as Epidemiology and Population Studies, Product Investigations, Development of Laboratory Techniques :: Diagnostics and Medical Technology which enable presentation of research or review works in overlapping areas of medicine and technology such us (but not limited to): medical diagnostics, medical imaging systems, computer simulation of health and disease processes, new medical devices, etc. Reviews and Special Reports - papers may be accepted on the basis that they provide a systematic, critical and up-to-date overview of literature pertaining to research or clinical topics. Meta-analyses are considered as reviews. A special attention will be paid to a teaching value of a review paper.
Medical Science Monitor is internationally indexed in Thomson-Reuters Web of Science, Journals Citation Report (JCR), Science Citation Index Expanded (SCI), Index Medicus MEDLINE, PubMed, PMC, EMBASE/Excerpta Medica, Chemical Abstracts CAS and Index Copernicus.
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