基于组织病理学图像的乳腺癌诊断,使用深度学习和生物启发优化。

IF 3.9 2区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
Venkata Nagaraju Thatha, M Ganesh Karthik, Venu Gopal Gaddam, D Pramodh Krishna, S Venkataramana, Kranthi Kumar Lella, Udayaraju Pamula
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引用次数: 0

摘要

乳腺癌诊断仍然是医学研究中的一个关键挑战,需要准确和自动化的检测方法。本研究引入了一种用于组织病理学图像分类的高级深度学习框架,该框架集成了AlexNet和门控循环单元(GRU)网络,并使用河马优化算法(HOA)进行了优化。最初,DenseNet-41从组织病理学图像中提取复杂的空间特征。这些特征然后由混合AlexNet-GRU模型处理,利用AlexNet的强大特征提取和GRU的顺序学习能力。采用HOA对超参数进行微调,确保模型性能最优。该方法在基准数据集(BreakHis和BACH)上进行了评估,实现了99.60%的分类准确率,超过了现有的最先进的模型。研究结果证明了将深度学习与生物优化技术相结合在乳腺癌检测中的有效性。这项研究为改善早期诊断和临床决策提供了一个强大的、计算效率高的框架,潜在地提高了患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Histopathological image based breast cancer diagnosis using deep learning and bio inspired optimization.

Histopathological image based breast cancer diagnosis using deep learning and bio inspired optimization.

Histopathological image based breast cancer diagnosis using deep learning and bio inspired optimization.

Histopathological image based breast cancer diagnosis using deep learning and bio inspired optimization.

Breast cancer diagnosis remains a crucial challenge in medical research, necessitating accurate and automated detection methods. This study introduces an advanced deep learning framework for histopathological image classification, integrating AlexNet and Gated Recurrent Unit (GRU) networks, optimized using the Hippopotamus Optimization Algorithm (HOA). Initially, DenseNet-41 extracts intricate spatial features from histopathological images. These features are then processed by the hybrid AlexNet-GRU model, leveraging AlexNet's robust feature extraction and GRU's sequential learning capabilities. HOA is employed to fine-tune hyperparameters, ensuring optimal model performance. The proposed approach is evaluated on benchmark datasets (BreakHis and BACH), achieving a classification accuracy of 99.60%, surpassing existing state-of-the-art models. The results demonstrate the efficacy of integrating deep learning with bio-inspired optimization techniques in breast cancer detection. This research offers a robust and computationally efficient framework for improving early diagnosis and clinical decision-making, potentially enhancing patient outcomes.

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来源期刊
Scientific Reports
Scientific Reports Natural Science Disciplines-
CiteScore
7.50
自引率
4.30%
发文量
19567
审稿时长
3.9 months
期刊介绍: We publish original research from all areas of the natural sciences, psychology, medicine and engineering. You can learn more about what we publish by browsing our specific scientific subject areas below or explore Scientific Reports by browsing all articles and collections. Scientific Reports has a 2-year impact factor: 4.380 (2021), and is the 6th most-cited journal in the world, with more than 540,000 citations in 2020 (Clarivate Analytics, 2021). •Engineering Engineering covers all aspects of engineering, technology, and applied science. It plays a crucial role in the development of technologies to address some of the world''s biggest challenges, helping to save lives and improve the way we live. •Physical sciences Physical sciences are those academic disciplines that aim to uncover the underlying laws of nature — often written in the language of mathematics. It is a collective term for areas of study including astronomy, chemistry, materials science and physics. •Earth and environmental sciences Earth and environmental sciences cover all aspects of Earth and planetary science and broadly encompass solid Earth processes, surface and atmospheric dynamics, Earth system history, climate and climate change, marine and freshwater systems, and ecology. It also considers the interactions between humans and these systems. •Biological sciences Biological sciences encompass all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants. •Health sciences The health sciences study health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.
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