E R Zulkarneev, A I Laishevtsev, I A Kiseleva, O G Efimova, A V Aleshkin
{"title":"噬菌体BF1354对被耐药沙门氏菌人工污染的鸡肉去污效果的研究。","authors":"E R Zulkarneev, A I Laishevtsev, I A Kiseleva, O G Efimova, A V Aleshkin","doi":"10.1007/s10517-025-06409-8","DOIUrl":null,"url":null,"abstract":"<p><p>Salmonella, the agent causing salmonellosis, is one of the most common food pathogens in the world. Bacteriophages are now considered as the most effective and environmentally friendly method to control pathogens in various food products. We evaluated the efficacy of Salmonella phage BF1354 in decontamination of chicken fillet samples artificially contaminated with antibiotic-resistant Salmonella. Sterile chicken fillet samples (5 × 5 cm<sup>2</sup>) were artificially contaminated with Salmonella Enteritidis and then treated with bacteriophage at a concentration of 10<sup>9</sup> PFU/ml. The samples were stored at 4°C for 10 days. The number of Salmonella on days 1, 6, and 10 of the experiment decreased by 2.1, 2, and 0.8 log(CFU/g), respectively, in comparison with the control. The results demonstrate the efficacy of bacteriophage BF1354 in reducing the number of Salmonella cells in chicken fillets at refrigerated storage temperatures.</p>","PeriodicalId":9331,"journal":{"name":"Bulletin of Experimental Biology and Medicine","volume":" ","pages":"744-749"},"PeriodicalIF":0.6000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Study of the Effectiveness of Bacteriophage BF1354 in the Decontamination of Chicken Meat Artificially Contaminated with an Antibiotic-Resistant Strain of Salmonella.\",\"authors\":\"E R Zulkarneev, A I Laishevtsev, I A Kiseleva, O G Efimova, A V Aleshkin\",\"doi\":\"10.1007/s10517-025-06409-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Salmonella, the agent causing salmonellosis, is one of the most common food pathogens in the world. Bacteriophages are now considered as the most effective and environmentally friendly method to control pathogens in various food products. We evaluated the efficacy of Salmonella phage BF1354 in decontamination of chicken fillet samples artificially contaminated with antibiotic-resistant Salmonella. Sterile chicken fillet samples (5 × 5 cm<sup>2</sup>) were artificially contaminated with Salmonella Enteritidis and then treated with bacteriophage at a concentration of 10<sup>9</sup> PFU/ml. The samples were stored at 4°C for 10 days. The number of Salmonella on days 1, 6, and 10 of the experiment decreased by 2.1, 2, and 0.8 log(CFU/g), respectively, in comparison with the control. The results demonstrate the efficacy of bacteriophage BF1354 in reducing the number of Salmonella cells in chicken fillets at refrigerated storage temperatures.</p>\",\"PeriodicalId\":9331,\"journal\":{\"name\":\"Bulletin of Experimental Biology and Medicine\",\"volume\":\" \",\"pages\":\"744-749\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of Experimental Biology and Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s10517-025-06409-8\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/5/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of Experimental Biology and Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10517-025-06409-8","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/30 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Study of the Effectiveness of Bacteriophage BF1354 in the Decontamination of Chicken Meat Artificially Contaminated with an Antibiotic-Resistant Strain of Salmonella.
Salmonella, the agent causing salmonellosis, is one of the most common food pathogens in the world. Bacteriophages are now considered as the most effective and environmentally friendly method to control pathogens in various food products. We evaluated the efficacy of Salmonella phage BF1354 in decontamination of chicken fillet samples artificially contaminated with antibiotic-resistant Salmonella. Sterile chicken fillet samples (5 × 5 cm2) were artificially contaminated with Salmonella Enteritidis and then treated with bacteriophage at a concentration of 109 PFU/ml. The samples were stored at 4°C for 10 days. The number of Salmonella on days 1, 6, and 10 of the experiment decreased by 2.1, 2, and 0.8 log(CFU/g), respectively, in comparison with the control. The results demonstrate the efficacy of bacteriophage BF1354 in reducing the number of Salmonella cells in chicken fillets at refrigerated storage temperatures.
期刊介绍：
Bulletin of Experimental Biology and Medicine presents original peer reviewed research papers and brief reports on priority new research results in physiology, biochemistry, biophysics, pharmacology, immunology, microbiology, genetics, oncology, etc. Novel trends in science are covered in new sections of the journal - Biogerontology and Human Ecology - that first appeared in 2005.
World scientific interest in stem cells prompted inclusion into Bulletin of Experimental Biology and Medicine a quarterly scientific journal Cell Technologies in Biology and Medicine (a new Russian Academy of Medical Sciences publication since 2005). It publishes only original papers from the leading research institutions on molecular biology of stem and progenitor cells, stem cell as the basis of gene therapy, molecular language of cell-to-cell communication, cytokines, chemokines, growth and other factors, pilot projects on clinical use of stem and progenitor cells.
The Russian Volume Year is published in English from April.
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