稳定二氧化氯、植物性口腔冲洗液和基多顿漱口水作为手术前漱口液抗菌效果的比较:一项随机临床试验。

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL
Annals of African Medicine Pub Date : 2025-07-01 Epub Date: 2025-05-30 DOI:10.4103/aam.aam_83_24
Tanuja Pericherla, Jayalakshmi Pandranki, Narsimha Rao V Vanga
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引用次数: 0

摘要

背景:由空气传播的生物材料组成的气溶胶,由于其潜在的致病性,在牙科手术中存在重大的生物危害风险。有效的感染控制措施对于在口腔预防和其他牙科活动中减轻这些风险至关重要。目的:该研究旨在评估两种市售漱口水的功效——一种含有稳定的二氧化氯(ClO2),另一种含有草药——作为手术前冲洗液,以及它们在儿童中的接受程度,为Kidodent漱口水提供替代选择。研究对象和方法:本研究纳入了60名9-14岁的个体,根据特定的纳入标准,每组15名参与者。在获得知情同意后,参与者在超声洗洁前用含氟三氯生漱口水(Kidodent)、稳定氯漱口水(Freshclor)、植物性口腔漱口水(BOR)或生理盐水冲洗。在口腔预防过程中,使用血琼脂平板捕捉空气中传播的细菌,孵育后计数菌落形成单位(cfu)。感官分析采用术后快感量表评估漱口水的可接受性。统计分析采用SPSS软件对数据进行分析,计算各变量的均数±标准差。单因素方差分析检验各组cfu的差异,随后进行事后Tukey检验。使用Kruskal-Wallis测试评估感觉反应。结果:研究发现,与生理盐水冲洗相比,BOR、Freshclor和Kidodent显著降低了细菌cfu (P < 0.001)。稳定ClO2和BOR的疗效与Kidodent相当(P < 0.05)。儿童倾向于稳定的ClO2 (n = 15;100%),然后是Kidodent (n = 13;86.67%),其中BOR最不受欢迎(n = 6;40%)。结论:本研究强调了术前漱口对降低牙科手术中污染风险的重要性(P < 0.001)。Oralife和Freshclor的疗效与Kidodent儿童漱口水相似(P < 0.05),分别提供了含有植物提取物和稳定ClO2的更安全的替代品。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative Evaluation of the Antimicrobial Efficacy of Stabilized Chlorine Dioxide, Botanical Oral Rinse, and Kidodent Mouthwash as Preprocedural Mouthrinse: A Randomized Clinical Trial.

Context: Aerosols composed of airborne biological material, present significant biohazard risks during dental procedures due to their potential pathogenicity. Effective infection control measures are essential to mitigate these risks during oral prophylaxis and other dental activities.

Aim: The study seeks to evaluate the efficacy of two commercially available mouthwashes - one with stabilized chlorine dioxide (ClO 2 ) and the other herbal based - as preprocedural rinses and their acceptance in children, offering alternative options to Kidodent mouthwash.

Subjects and methods: The study included 60 individuals aged 9-14 years, with 15 participants allocated to each group based on specific inclusion criteria. After obtaining informed consent, participants rinsed with either with fluoride-triclosan-based mouthwash (Kidodent), stabilized ClO 2 mouthwash (Freshclor), botanical oral rinse (BOR) (Oralife), or saline before ultrasonic scaling. Blood agar plates were used to capture airborne bacteria during oral prophylaxis, and colony-forming units (CFUs) were counted after incubation. Sensory analysis assessed mouthwash acceptability using a postoperative hedonic scale.

Statistical analysis used: SPSS software analyzed the data, computing mean ± standard deviation for each variable. One-way ANOVA tested group differences in CFUs, followed by post hoc Tukey's testing. Sensory responses were assessed using the Kruskal-Wallis test.

Results: The study found that BOR, Freshclor, and Kidodent significantly reduced bacterial CFUs compared to normal saline rinse ( P < 0.001). Stabilized ClO 2 and BOR were as effective as Kidodent ( P > 0.05). Children favored stabilized ClO 2 ( n = 15; 100%) and then Kidodent ( n = 13; 86.67%), with BOR being the least favored ( n = 6; 40%).

Conclusions: The research underscores the significance of preprocedural mouthrinses in reducing contamination risks during dental procedures ( P < 0.001). Oralife and Freshclor exhibit efficacy similar to Kidodent mouthwash for children ( P > 0.05), offering safer alternatives containing botanical extracts and stabilized ClO 2 , respectively.

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来源期刊
Annals of African Medicine
Annals of African Medicine MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
31
期刊介绍: The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.
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