Joon Yau Leong, Maria J. D'Amico, Courtney E. Capella, Leonard G. Gomella, Joseph K. Izes
{"title":"机器人辅助腹腔镜根治性前列腺切除术后Port site转移:通过前列腺特异性膜抗原(PSMA)靶向18F-DCFPyL PET/CT诊断","authors":"Joon Yau Leong, Maria J. D'Amico, Courtney E. Capella, Leonard G. Gomella, Joseph K. Izes","doi":"10.1016/j.eucr.2025.103082","DOIUrl":null,"url":null,"abstract":"<div><div>We present a case of port site metastasis (PSM) that was identified in an 82-year-old man with an elevated prostate-specific antigen (PSA) to 3.9 ng/mL, concerning for biochemical recurrence after robotic-assisted radical prostatectomy, adjuvant radiation, and six months of androgen deprivation therapy with an undetectable PSA post-treatment over 10 years ago. A 2.1 cm solitary tracer avid nodule on the right lateral abdominal wall with no other evidence of recurrence or metastatic disease was found on prostate-specific membrane antigen (PSMA)–targeted <sup>18</sup>F-DCFPyL PET/CT scan. The patient underwent local excision of this metastatic lesion, and final pathology revealed metastatic prostatic adenocarcinoma.</div></div>","PeriodicalId":38188,"journal":{"name":"Urology Case Reports","volume":"61 ","pages":"Article 103082"},"PeriodicalIF":0.5000,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Port site metastasis after robotic assisted laparoscopic radical prostatectomy: Diagnosis via prostate-specific membrane antigen (PSMA)-targeted 18F-DCFPyL PET/CT\",\"authors\":\"Joon Yau Leong, Maria J. D'Amico, Courtney E. Capella, Leonard G. Gomella, Joseph K. Izes\",\"doi\":\"10.1016/j.eucr.2025.103082\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We present a case of port site metastasis (PSM) that was identified in an 82-year-old man with an elevated prostate-specific antigen (PSA) to 3.9 ng/mL, concerning for biochemical recurrence after robotic-assisted radical prostatectomy, adjuvant radiation, and six months of androgen deprivation therapy with an undetectable PSA post-treatment over 10 years ago. A 2.1 cm solitary tracer avid nodule on the right lateral abdominal wall with no other evidence of recurrence or metastatic disease was found on prostate-specific membrane antigen (PSMA)–targeted <sup>18</sup>F-DCFPyL PET/CT scan. The patient underwent local excision of this metastatic lesion, and final pathology revealed metastatic prostatic adenocarcinoma.</div></div>\",\"PeriodicalId\":38188,\"journal\":{\"name\":\"Urology Case Reports\",\"volume\":\"61 \",\"pages\":\"Article 103082\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-05-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214442025001536\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214442025001536","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
我们报告一例port site metastasis (PSM),确诊于一名82岁男性,其前列腺特异性抗原(PSA)升高至3.9 ng/mL,在机器人辅助根治性前列腺切除术,辅助放疗和6个月的雄激素剥夺治疗后,PSA在治疗10多年后未检测到,这与生化复发有关。在前列腺特异性膜抗原(PSMA)靶向的18F-DCFPyL PET/CT扫描中,在右侧腹壁发现2.1 cm孤立示踪性结节,无其他复发或转移性疾病的证据。患者接受局部切除转移灶,最终病理显示转移性前列腺腺癌。
Port site metastasis after robotic assisted laparoscopic radical prostatectomy: Diagnosis via prostate-specific membrane antigen (PSMA)-targeted 18F-DCFPyL PET/CT
We present a case of port site metastasis (PSM) that was identified in an 82-year-old man with an elevated prostate-specific antigen (PSA) to 3.9 ng/mL, concerning for biochemical recurrence after robotic-assisted radical prostatectomy, adjuvant radiation, and six months of androgen deprivation therapy with an undetectable PSA post-treatment over 10 years ago. A 2.1 cm solitary tracer avid nodule on the right lateral abdominal wall with no other evidence of recurrence or metastatic disease was found on prostate-specific membrane antigen (PSMA)–targeted 18F-DCFPyL PET/CT scan. The patient underwent local excision of this metastatic lesion, and final pathology revealed metastatic prostatic adenocarcinoma.