{"title":"免疫缺陷患者巨细胞病毒性肺炎并发曲霉菌感染的死亡病例。","authors":"Kunlun Huang, Shaosen Chen","doi":"10.1093/omcr/omaf060","DOIUrl":null,"url":null,"abstract":"<p><p><b>Introduction</b>: Cytomegalovirus (CMV) disease is common among transplant patients, who are also prone to secondary bacterial or fungal infections. However, coinfection in immunodeficient patients is rare and often makes diagnosis and treatment challenging. <b>Patient concerns</b>: The patient was an older woman with low immune function but was not a transplant patient. <b>Diagnosis</b>: The patient presented with complaints of fever and shortness of breath for 1 day. After a medical evaluation, she was diagnosed with CMV infection and fungal pneumonia. <b>Interventions</b>: The patient received ceftriaxone + human immunoglobulin + voriconazole treatment. <b>Outcome</b>: The patient's condition deteriorated and she eventually died of myocardial infarction. <b>Conclusion</b>: For immunocompromised patients, early recognition of coinfections, along with combination medication, maybe a key factor in improving prognosis.</p>","PeriodicalId":45318,"journal":{"name":"Oxford Medical Case Reports","volume":"2025 5","pages":"omaf060"},"PeriodicalIF":0.5000,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118047/pdf/","citationCount":"0","resultStr":"{\"title\":\"A fatal case of cytomegalovirus pneumonia with coexisting <i>aspergillus</i> infection in a immunodeficient patient.\",\"authors\":\"Kunlun Huang, Shaosen Chen\",\"doi\":\"10.1093/omcr/omaf060\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Introduction</b>: Cytomegalovirus (CMV) disease is common among transplant patients, who are also prone to secondary bacterial or fungal infections. However, coinfection in immunodeficient patients is rare and often makes diagnosis and treatment challenging. <b>Patient concerns</b>: The patient was an older woman with low immune function but was not a transplant patient. <b>Diagnosis</b>: The patient presented with complaints of fever and shortness of breath for 1 day. After a medical evaluation, she was diagnosed with CMV infection and fungal pneumonia. <b>Interventions</b>: The patient received ceftriaxone + human immunoglobulin + voriconazole treatment. <b>Outcome</b>: The patient's condition deteriorated and she eventually died of myocardial infarction. <b>Conclusion</b>: For immunocompromised patients, early recognition of coinfections, along with combination medication, maybe a key factor in improving prognosis.</p>\",\"PeriodicalId\":45318,\"journal\":{\"name\":\"Oxford Medical Case Reports\",\"volume\":\"2025 5\",\"pages\":\"omaf060\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-05-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12118047/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oxford Medical Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/omcr/omaf060\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/5/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oxford Medical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/omcr/omaf060","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
A fatal case of cytomegalovirus pneumonia with coexisting aspergillus infection in a immunodeficient patient.
Introduction: Cytomegalovirus (CMV) disease is common among transplant patients, who are also prone to secondary bacterial or fungal infections. However, coinfection in immunodeficient patients is rare and often makes diagnosis and treatment challenging. Patient concerns: The patient was an older woman with low immune function but was not a transplant patient. Diagnosis: The patient presented with complaints of fever and shortness of breath for 1 day. After a medical evaluation, she was diagnosed with CMV infection and fungal pneumonia. Interventions: The patient received ceftriaxone + human immunoglobulin + voriconazole treatment. Outcome: The patient's condition deteriorated and she eventually died of myocardial infarction. Conclusion: For immunocompromised patients, early recognition of coinfections, along with combination medication, maybe a key factor in improving prognosis.
期刊介绍:
Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.