确保获得新的供体心脏保存方式。

IF 6.4 1区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Joseph B Lerman, Katherine D Marapese, Amber R Johnson, Ian R Jamieson, Jeffrey E Keenan, Jacob N Schroder, Adam D DeVore, Chetan B Patel
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引用次数: 0

摘要

尽管早期心脏病的治疗有所改善,但在美国,需要心脏移植的患者人数仍在继续增加。幸运的是,获取和保存供体心脏的新方法,包括体外心脏灌注(EVHP)和控制低温保存的使用,使心脏移植的数量增加。特别是,EVHP促进了循环性死亡(DCD)后捐赠的利用增加,以及对地理距离增加和标准(边缘)捐赠者的捐赠心脏的使用增加。然而,这种保存技术的使用伴随着供体心脏采购成本的显著增加和供体器官采购服务行业的出现。我们的目的是概述心脏捐赠成本的上升,探讨这种增长的原因,并讨论潜在的解决方案,以推动成本节约和增加心脏移植的可及性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ensuring Access to Novel Donor Heart Preservation Modalities.

Despite improvements in managing earlier stage heart disease, the population of patients needing heart transplants continues to increase in the United States. Fortunately, novel methods of procuring and preserving donor hearts, including the use of ex-vivo heart perfusion (EVHP) and controlled hypothermic preservation, have enabled a rise in heart transplantation. In particular, EVHP has contributed to increased utilization of donation after circulatory death (DCD), as well as enhanced use of donor hearts from increased geographic distances and extended criteria (marginal) donors. The use of such preservation technologies, however, has coincided with a significant increase in the cost of donor heart procurement and the advent of a donor organ procurement services industry. We aim to provide an overview on the rising costs of heart donation, explore the causes of such increase, and discuss potential solutions to drive both cost savings and increased access to heart transplantation.

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来源期刊
CiteScore
10.10
自引率
6.70%
发文量
1667
审稿时长
69 days
期刊介绍: The Journal of Heart and Lung Transplantation, the official publication of the International Society for Heart and Lung Transplantation, brings readers essential scholarly and timely information in the field of cardio-pulmonary transplantation, mechanical and biological support of the failing heart, advanced lung disease (including pulmonary vascular disease) and cell replacement therapy. Importantly, the journal also serves as a medium of communication of pre-clinical sciences in all these rapidly expanding areas.
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