揭示曲烷氧啶除草剂及其制剂在天然水体中的光降解:转化产物的结构解析和毒性评价

IF 6.1 2区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES
María José Patiño-Ropero , Juan Carlos Nieto-Carmona , María Cobos-Escudero , Al Mokhtar Lamsabhi , Manuel Alcamí , José Luis Alonso-Prados , Pilar Sandín-España
{"title":"揭示曲烷氧啶除草剂及其制剂在天然水体中的光降解:转化产物的结构解析和毒性评价","authors":"María José Patiño-Ropero ,&nbsp;Juan Carlos Nieto-Carmona ,&nbsp;María Cobos-Escudero ,&nbsp;Al Mokhtar Lamsabhi ,&nbsp;Manuel Alcamí ,&nbsp;José Luis Alonso-Prados ,&nbsp;Pilar Sandín-España","doi":"10.1016/j.ecoenv.2025.118409","DOIUrl":null,"url":null,"abstract":"<div><div>Pesticide degradation products (DPs), as emerging contaminants, are being detected in aquatic environments due to the widespread use of their active substances and pose potential risks to aquatic ecology and human health. However, their identification is challenging due to the many environmental conditions that influence their degradation processes. The photodegradation of the herbicide tralkoxydim and its formulation has been studied in ultrapure, spring and river waters and has shown rapid degradation. The photodegradation of tralkoxydim was slower in natural water and in the presence of humic acids (HA) than in ultrapure water, with half-lives of 5.1 h for river water and 1.1 h for ultrapure water. For the first time, three degradation products were identified in aquatic media using HPLC-TOF-MS/MS. These include photoisomerization, photolysis of the N-O bond of the oxime resulting in the tralkoxydim imine (major DP), and cyclization leading to tralkoxydim oxazole. Quantitative structure-activity relationship (QSAR) models were employed to approximate the potential ecotoxicological and environmental impacts of tralkoxydim and its DPs. Additionally, the toxicity of the isolated DPs was evaluated using a standard microtest bioassay with <em>Vibrio fischeri</em> bacteria. The results show that tralkoxydim imine and tralkoxydim oxazole exhibit high toxicity.</div></div>","PeriodicalId":303,"journal":{"name":"Ecotoxicology and Environmental Safety","volume":"299 ","pages":"Article 118409"},"PeriodicalIF":6.1000,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Unveiling the photodegradation of tralkoxydim herbicide and its formulation in natural waters: Structural elucidation of transformation products and toxicity assessment\",\"authors\":\"María José Patiño-Ropero ,&nbsp;Juan Carlos Nieto-Carmona ,&nbsp;María Cobos-Escudero ,&nbsp;Al Mokhtar Lamsabhi ,&nbsp;Manuel Alcamí ,&nbsp;José Luis Alonso-Prados ,&nbsp;Pilar Sandín-España\",\"doi\":\"10.1016/j.ecoenv.2025.118409\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Pesticide degradation products (DPs), as emerging contaminants, are being detected in aquatic environments due to the widespread use of their active substances and pose potential risks to aquatic ecology and human health. However, their identification is challenging due to the many environmental conditions that influence their degradation processes. The photodegradation of the herbicide tralkoxydim and its formulation has been studied in ultrapure, spring and river waters and has shown rapid degradation. The photodegradation of tralkoxydim was slower in natural water and in the presence of humic acids (HA) than in ultrapure water, with half-lives of 5.1 h for river water and 1.1 h for ultrapure water. For the first time, three degradation products were identified in aquatic media using HPLC-TOF-MS/MS. These include photoisomerization, photolysis of the N-O bond of the oxime resulting in the tralkoxydim imine (major DP), and cyclization leading to tralkoxydim oxazole. Quantitative structure-activity relationship (QSAR) models were employed to approximate the potential ecotoxicological and environmental impacts of tralkoxydim and its DPs. Additionally, the toxicity of the isolated DPs was evaluated using a standard microtest bioassay with <em>Vibrio fischeri</em> bacteria. The results show that tralkoxydim imine and tralkoxydim oxazole exhibit high toxicity.</div></div>\",\"PeriodicalId\":303,\"journal\":{\"name\":\"Ecotoxicology and Environmental Safety\",\"volume\":\"299 \",\"pages\":\"Article 118409\"},\"PeriodicalIF\":6.1000,\"publicationDate\":\"2025-05-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ecotoxicology and Environmental Safety\",\"FirstCategoryId\":\"93\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0147651325007456\",\"RegionNum\":2,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENVIRONMENTAL SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ecotoxicology and Environmental Safety","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0147651325007456","RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 0

摘要

农药降解产物作为一种新兴污染物,由于其活性物质的广泛使用,在水生环境中不断被发现,并对水生生态和人类健康构成潜在风险。然而,由于影响其降解过程的许多环境条件,它们的鉴定具有挑战性。研究了除草剂曲烷氧啶及其制剂在超纯水、泉水和河水中的光降解效果,发现其降解速度快。天然水和腐殖酸(HA)存在下,tralkoxydim的光降解速度比超纯水慢,河水的半衰期为5.1 h,超纯水的半衰期为1.1 h。采用HPLC-TOF-MS/MS技术,首次在水生介质中鉴定出3种降解产物。这些反应包括光异构化,肟的N-O键的光解,产生三烷基氧基亚胺(主要DP),以及环化,产生三烷基氧基恶唑。采用定量构效关系(Quantitative structure-activity relationship, QSAR)模型估计了曲烷氧啶及其DPs的潜在生态毒理学和环境影响。此外,分离的DPs的毒性是用标准的微试验生物测定法与费氏弧菌细菌进行评估。结果表明,曲烷氧基亚胺和曲烷氧基恶唑具有较高的毒性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unveiling the photodegradation of tralkoxydim herbicide and its formulation in natural waters: Structural elucidation of transformation products and toxicity assessment
Pesticide degradation products (DPs), as emerging contaminants, are being detected in aquatic environments due to the widespread use of their active substances and pose potential risks to aquatic ecology and human health. However, their identification is challenging due to the many environmental conditions that influence their degradation processes. The photodegradation of the herbicide tralkoxydim and its formulation has been studied in ultrapure, spring and river waters and has shown rapid degradation. The photodegradation of tralkoxydim was slower in natural water and in the presence of humic acids (HA) than in ultrapure water, with half-lives of 5.1 h for river water and 1.1 h for ultrapure water. For the first time, three degradation products were identified in aquatic media using HPLC-TOF-MS/MS. These include photoisomerization, photolysis of the N-O bond of the oxime resulting in the tralkoxydim imine (major DP), and cyclization leading to tralkoxydim oxazole. Quantitative structure-activity relationship (QSAR) models were employed to approximate the potential ecotoxicological and environmental impacts of tralkoxydim and its DPs. Additionally, the toxicity of the isolated DPs was evaluated using a standard microtest bioassay with Vibrio fischeri bacteria. The results show that tralkoxydim imine and tralkoxydim oxazole exhibit high toxicity.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
12.10
自引率
5.90%
发文量
1234
审稿时长
88 days
期刊介绍: Ecotoxicology and Environmental Safety is a multi-disciplinary journal that focuses on understanding the exposure and effects of environmental contamination on organisms including human health. The scope of the journal covers three main themes. The topics within these themes, indicated below, include (but are not limited to) the following: Ecotoxicology、Environmental Chemistry、Environmental Safety etc.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信