青霉属植物中罕见二聚愈创木烷及其单体的发现。

IF 3.4 2区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Phytochemistry Pub Date : 2025-05-26 DOI:10.1016/j.phytochem.2025.114560

Tian-Ming Lv , Zhi‐Yuan Li , Li-Li Lou , Le Chen , Xiao‐Xiao Huang , Shao‐Jiang Song

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引用次数: 0

摘要

从达芙妮青霉中分离到2个未被描述的二聚愈创烷（1-2），共享7/5/5/5/7个支架，以及3个未被描述的愈创烷型倍半萜类（3-5）。通过核磁共振光谱分析和量子化学计算确定了它们的结构。对SH-SY5Y细胞氧化损伤的神经保护作用进行了测试，结果显示4和5的潜在神经保护作用分别为70.38%和61.86%。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Discovery of the rare dimeric guaianes and their monomers from the Daphne penicillata Rehd

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Discovery of the rare dimeric guaianes and their monomers from the Daphne penicillata Rehd

Two previously undescribed dimeric guaianes (1–2) sharing 7/5/5/5/7 scaffolds and three undescribed guaiane-type sesquiterpenoids (3–5) were isolated from the Daphne penicillata Rehd. Their structures were identified by NMR spectroscopic analysis, and quantum chemical calculations. The neuroprotective activities to protect SH-SY5Y cells from oxidave damage were tested and 4 and 5 exhibited potential neuroprotective effects at 70.38 % and 61.86 %.

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来源期刊

Phytochemistry 生物-植物科学

CiteScore

6.40

自引率

7.90%

发文量

443

审稿时长

39 days

期刊介绍： Phytochemistry is a leading international journal publishing studies of plant chemistry, biochemistry, molecular biology and genetics, structure and bioactivities of phytochemicals, including ''-omics'' and bioinformatics/computational biology approaches. Phytochemistry is a primary source for papers dealing with phytochemicals, especially reports concerning their biosynthesis, regulation, and biological properties both in planta and as bioactive principles. Articles are published online as soon as possible as Articles-in-Press and in 12 volumes per year. Occasional topic-focussed special issues are published composed of papers from invited authors.