基于神经网络和表面肌电图的青少年特发性脊柱侧凸患者后schroth Cobb角变化预测。

IF 4.3 3区 工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Frontiers in Bioengineering and Biotechnology Pub Date : 2025-05-14 eCollection Date: 2025-01-01 DOI:10.3389/fbioe.2025.1570022
Shuguang Yin, Jiangang Chen, Peng Yan
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引用次数: 0

摘要

目的:建立一种整合表面肌电(sEMG)信号的颞-卷积- lstm (TCN-LSTM)混合模型,用于预测青少年特发性脊柱侧凸(AIS)患者schroth Cobb角后进展,从而为个性化治疗提供准确反馈。方法:共纳入143例AIS患者。设计了一套系统的施罗斯运动训练方案。收集特定肌肉和Cobb角测量的表面肌电信号数据。构建了一个集时间卷积网络(TCN)、长短期记忆(LSTM)层和特征向量为一体的神经网络模型。比较了四种预测模型:TCN-LSTM混合模型、TCN、LSTM和支持向量回归(SVR)。结果:TCN-LSTM混合模型表现出优越的性能,Cobb角-胸(Cobb角- t)预测精度达到R2 = 0.63(基线)和0.69(第24周),总体R2 = 0.74。对于Cobb角-腰椎(Cobb角- l),准确率R2 = 0.61(基线)和0.65(第24周),总体R2 = 0.73。SVR模型表现最差(R2 < 0.12)。结论:TCN-LSTM混合模型能准确预测AIS患者Schroth运动时Cobb角的变化,尤其是长期预测。为临床治疗提供实时反馈,有助于优化治疗方案,为评价AIS患者Schroth矫正练习的有效性提供了一种新的预测方法和参考依据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prediction of post-Schroth Cobb angle changes in adolescent idiopathic scoliosis patients based on neural networks and surface electromyography.

Introduction: To develop a temporal-convolutional-LSTM (TCN-LSTM) hybrid model integrating surface electromyography (sEMG) signals for forecasting post-Schroth Cobb angle progression in adolescent idiopathic scoliosis (AIS) patients, thereby offering accurate feedback for personalized treatment.

Methodology: A total of 143 AIS patients were included. A systematic Schroth exercise training program was designed. sEMG data from specific muscles and Cobb angle measurements were collected. A neural network model integrating Temporal Convolutional Network (TCN), Long Short-Term Memory (LSTM) layers, and feature vectors was constructed. Four prediction models were compared: TCN-LSTM hybrid model, TCN, LSTM, and Support Vector Regression (SVR).

Results: The TCN-LSTM hybrid model demonstrated superior performance, with Cobb angle-Thoracic (Cobb Angle-T) prediction accuracy reaching R2 = 0.63 (baseline) and 0.69 (Week 24), achieving overall R2 = 0.74. For Cobb angle-Lumbar (Cobb Angle-L), accuracy was R2 = 0.61 (baseline) and 0.65 (Week 24), with overall R2 = 0.73. The SVR model showed lowest performance (R2 < 0.12).

Conclusion: The TCN-LSTM hybrid model can precisely predict Cobb angle changes in AIS patients during Schroth exercises, especially in long-term predictions. It provides real-time feedback for clinical treatment and contributes to optimizing treatment plans, presenting a novel prediction approach and reference basis for evaluating the effectiveness of Schroth correction exercises in AIS patients.

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来源期刊
Frontiers in Bioengineering and Biotechnology
Frontiers in Bioengineering and Biotechnology Chemical Engineering-Bioengineering
CiteScore
8.30
自引率
5.30%
发文量
2270
审稿时长
12 weeks
期刊介绍: The translation of new discoveries in medicine to clinical routine has never been easy. During the second half of the last century, thanks to the progress in chemistry, biochemistry and pharmacology, we have seen the development and the application of a large number of drugs and devices aimed at the treatment of symptoms, blocking unwanted pathways and, in the case of infectious diseases, fighting the micro-organisms responsible. However, we are facing, today, a dramatic change in the therapeutic approach to pathologies and diseases. Indeed, the challenge of the present and the next decade is to fully restore the physiological status of the diseased organism and to completely regenerate tissue and organs when they are so seriously affected that treatments cannot be limited to the repression of symptoms or to the repair of damage. This is being made possible thanks to the major developments made in basic cell and molecular biology, including stem cell science, growth factor delivery, gene isolation and transfection, the advances in bioengineering and nanotechnology, including development of new biomaterials, biofabrication technologies and use of bioreactors, and the big improvements in diagnostic tools and imaging of cells, tissues and organs. In today`s world, an enhancement of communication between multidisciplinary experts, together with the promotion of joint projects and close collaborations among scientists, engineers, industry people, regulatory agencies and physicians are absolute requirements for the success of any attempt to develop and clinically apply a new biological therapy or an innovative device involving the collective use of biomaterials, cells and/or bioactive molecules. “Frontiers in Bioengineering and Biotechnology” aspires to be a forum for all people involved in the process by bridging the gap too often existing between a discovery in the basic sciences and its clinical application.
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