古细菌s层的生物发生、功能和进化

IF 4.3 2区生物学 Q1 CELL BIOLOGY

Current Opinion in Cell Biology Pub Date : 2025-05-29 DOI:10.1016/j.ceb.2025.102534

Shamphavi Sivabalasarma , Marleen van Wolferen , Sonja-Verena Albers , Arthur Charles-Orszag

{"title":"古细菌s层的生物发生、功能和进化","authors":"Shamphavi Sivabalasarma , Marleen van Wolferen , Sonja-Verena Albers , Arthur Charles-Orszag","doi":"10.1016/j.ceb.2025.102534","DOIUrl":null,"url":null,"abstract":"<div><div>The archaeal S-layer represents one of the most ancient and versatile cell surface structures, playing critical roles in maintaining cellular integrity, mediating environmental interactions, and enabling cellular flexibility. Recent advances in structural biology, including cryo-electron microscopy and computational tools like AlphaFold, have unveiled the structural intricacies and diversity of these proteinaceous layers. This review highlights the biogenesis, structural assembly, evolutionary adaptations, and functional roles of archaeal S-layers, focusing on model organisms such as <em>Sulfolobus acidocaldarius</em> and <em>Haloferax volcanii</em>. Additionally, we discuss outstanding questions and future directions for the study of archaeal cell envelopes.</div></div>","PeriodicalId":50608,"journal":{"name":"Current Opinion in Cell Biology","volume":"95 ","pages":"Article 102534"},"PeriodicalIF":4.3000,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Biogenesis, function and evolution of the archaeal S-layer\",\"authors\":\"Shamphavi Sivabalasarma , Marleen van Wolferen , Sonja-Verena Albers , Arthur Charles-Orszag\",\"doi\":\"10.1016/j.ceb.2025.102534\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The archaeal S-layer represents one of the most ancient and versatile cell surface structures, playing critical roles in maintaining cellular integrity, mediating environmental interactions, and enabling cellular flexibility. Recent advances in structural biology, including cryo-electron microscopy and computational tools like AlphaFold, have unveiled the structural intricacies and diversity of these proteinaceous layers. This review highlights the biogenesis, structural assembly, evolutionary adaptations, and functional roles of archaeal S-layers, focusing on model organisms such as <em>Sulfolobus acidocaldarius</em> and <em>Haloferax volcanii</em>. Additionally, we discuss outstanding questions and future directions for the study of archaeal cell envelopes.</div></div>\",\"PeriodicalId\":50608,\"journal\":{\"name\":\"Current Opinion in Cell Biology\",\"volume\":\"95 \",\"pages\":\"Article 102534\"},\"PeriodicalIF\":4.3000,\"publicationDate\":\"2025-05-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Opinion in Cell Biology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0955067425000729\",\"RegionNum\":2,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CELL BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Cell Biology","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0955067425000729","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CELL BIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

古细菌s层代表了最古老和多功能的细胞表面结构之一，在维持细胞完整性，调节环境相互作用和实现细胞灵活性方面发挥着关键作用。结构生物学的最新进展，包括低温电子显微镜和像AlphaFold这样的计算工具，揭示了这些蛋白质层结构的复杂性和多样性。本文综述了古细菌s层的生物起源、结构组合、进化适应和功能作用，重点介绍了酸性硫藻（Sulfolobus acidocalarius）和火山盐藻（Haloferax volcanii）等模式生物。此外，我们还讨论了古细菌细胞包膜研究中存在的问题和未来的研究方向。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Biogenesis, function and evolution of the archaeal S-layer

The archaeal S-layer represents one of the most ancient and versatile cell surface structures, playing critical roles in maintaining cellular integrity, mediating environmental interactions, and enabling cellular flexibility. Recent advances in structural biology, including cryo-electron microscopy and computational tools like AlphaFold, have unveiled the structural intricacies and diversity of these proteinaceous layers. This review highlights the biogenesis, structural assembly, evolutionary adaptations, and functional roles of archaeal S-layers, focusing on model organisms such as Sulfolobus acidocaldarius and Haloferax volcanii. Additionally, we discuss outstanding questions and future directions for the study of archaeal cell envelopes.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Current Opinion in Cell Biology 生物-细胞生物学

CiteScore

14.60

自引率

1.30%

发文量

审稿时长

93 days

期刊介绍： Current Opinion in Cell Biology (COCEBI) is a highly respected journal that specializes in publishing authoritative, comprehensive, and systematic reviews in the field of cell biology. The journal's primary aim is to provide a clear and readable synthesis of the latest advances in cell biology, helping specialists stay current with the rapidly evolving field. Expert authors contribute to the journal by annotating and highlighting the most significant papers from the extensive body of research published annually, offering valuable insights and saving time for readers by distilling key findings. COCEBI is part of the Current Opinion and Research (CO+RE) suite of journals, which leverages the legacy of editorial excellence, high impact, and global reach to ensure that the journal is a widely read resource integral to scientists' workflow. It is published by Elsevier, a publisher known for its commitment to excellence in scientific publishing and the communication of reproducible biomedical research aimed at improving human health. The journal's content is designed to be an invaluable resource for a diverse audience, including researchers, lecturers, teachers, professionals, policymakers, and students.