{"title":"在嗜热温度下操作:气体发酵过程中被低估的资产","authors":"Hariklia N Gavala, Ioannis V Skiadas","doi":"10.1016/j.copbio.2025.103319","DOIUrl":null,"url":null,"abstract":"<div><div>Gas fermentation technology presents great potential for enhancing the transition of our society to a sustainable era and alleviating the climate crisis. Scalability, robustness, and economic viability are decisive factors for successfully bringing emerging technologies on a commercial scale. Compared to traditional liquid phase fermentation, gas fermentation comes with additional challenges that mainly stem from gas–liquid mass transfer limitations. Operation at moderately elevated temperatures (50–60 °C) enhances the mass transfer rate and consequently productivity, thus improving the economic indicators. However, the scarcity of studies at the thermophilic range that could set the foundation for further scaling-up for products other than biomethane is noticeable. This review summarizes progress in the last 10 years regarding thermophilic CO<sub>2</sub> and syngas fermentation and discusses a way forward to improving the competitiveness of gas fermentation technology via operation at elevated temperature.</div></div>","PeriodicalId":10833,"journal":{"name":"Current opinion in biotechnology","volume":"94 ","pages":"Article 103319"},"PeriodicalIF":7.1000,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Operation at thermophilic temperatures: an underestimated asset for gas fermentation processes\",\"authors\":\"Hariklia N Gavala, Ioannis V Skiadas\",\"doi\":\"10.1016/j.copbio.2025.103319\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Gas fermentation technology presents great potential for enhancing the transition of our society to a sustainable era and alleviating the climate crisis. Scalability, robustness, and economic viability are decisive factors for successfully bringing emerging technologies on a commercial scale. Compared to traditional liquid phase fermentation, gas fermentation comes with additional challenges that mainly stem from gas–liquid mass transfer limitations. Operation at moderately elevated temperatures (50–60 °C) enhances the mass transfer rate and consequently productivity, thus improving the economic indicators. However, the scarcity of studies at the thermophilic range that could set the foundation for further scaling-up for products other than biomethane is noticeable. This review summarizes progress in the last 10 years regarding thermophilic CO<sub>2</sub> and syngas fermentation and discusses a way forward to improving the competitiveness of gas fermentation technology via operation at elevated temperature.</div></div>\",\"PeriodicalId\":10833,\"journal\":{\"name\":\"Current opinion in biotechnology\",\"volume\":\"94 \",\"pages\":\"Article 103319\"},\"PeriodicalIF\":7.1000,\"publicationDate\":\"2025-05-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current opinion in biotechnology\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0958166925000631\",\"RegionNum\":2,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current opinion in biotechnology","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0958166925000631","RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Operation at thermophilic temperatures: an underestimated asset for gas fermentation processes
Gas fermentation technology presents great potential for enhancing the transition of our society to a sustainable era and alleviating the climate crisis. Scalability, robustness, and economic viability are decisive factors for successfully bringing emerging technologies on a commercial scale. Compared to traditional liquid phase fermentation, gas fermentation comes with additional challenges that mainly stem from gas–liquid mass transfer limitations. Operation at moderately elevated temperatures (50–60 °C) enhances the mass transfer rate and consequently productivity, thus improving the economic indicators. However, the scarcity of studies at the thermophilic range that could set the foundation for further scaling-up for products other than biomethane is noticeable. This review summarizes progress in the last 10 years regarding thermophilic CO2 and syngas fermentation and discusses a way forward to improving the competitiveness of gas fermentation technology via operation at elevated temperature.
期刊介绍:
Current Opinion in Biotechnology (COBIOT) is renowned for publishing authoritative, comprehensive, and systematic reviews. By offering clear and readable syntheses of current advances in biotechnology, COBIOT assists specialists in staying updated on the latest developments in the field. Expert authors annotate the most noteworthy papers from the vast array of information available today, providing readers with valuable insights and saving them time.
As part of the Current Opinion and Research (CO+RE) suite of journals, COBIOT is accompanied by the open-access primary research journal, Current Research in Biotechnology (CRBIOT). Leveraging the editorial excellence, high impact, and global reach of the Current Opinion legacy, CO+RE journals ensure they are widely read resources integral to scientists' workflows.
COBIOT is organized into themed sections, each reviewed once a year. These themes cover various areas of biotechnology, including analytical biotechnology, plant biotechnology, food biotechnology, energy biotechnology, environmental biotechnology, systems biology, nanobiotechnology, tissue, cell, and pathway engineering, chemical biotechnology, and pharmaceutical biotechnology.