血红素催化的n -氧化物还原及其在化学发光探针检测血红素和血红蛋白中的应用

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-05-29 DOI:10.1039/D5CC02085A

Pengfei Lei, Chen Chen, Xuehui Liu, Shuang Wang, Jing Li, Xiang Lv and Chong-Jing Zhang

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引用次数: 0

摘要

催化反应被广泛用于放大检测信号。在这里，我们提出了血红素介导的n -氧化物还原的被忽视的催化性质，这指导了基于化学发光的探针（CCP-1）的发展。该探针对游离血红素和血红蛋白表现出前所未有的相似反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Heme-catalyzed reduction of N-oxide and its application to sensing heme and hemoglobin via a chemiluminescent probe†

查看原文本刊更多论文

Heme-catalyzed reduction of N-oxide and its application to sensing heme and hemoglobin via a chemiluminescent probe†

Catalytic reactions are extensively employed to amplify detection signals. Here, we present the overlooked catalytic nature of the heme-mediated reduction of N-oxide and the use of this process to guide the development of a chemiluminescence-based probe (CCP-1). The probe showed, unprecedentedly, similar responses towards free heme and hemoglobin.

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.