超临界CO2发泡制备双功能单体控制埃及伊蚊

IF 7.1 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

ACS Sustainable Chemistry & Engineering Pub Date : 2025-05-29 DOI:10.1021/acssuschemeng.5c01126

Glaucia Burin, Vinícius Pires, Elaine C.M. Cabral-Albuquerque, Silvio A.B. Vieira de Melo, Gabriel B. Faierstein, Rosângela M.R. Barbosa, José Miranda, Fabio R. Formiga, Hermínio C. de Sousa, Mara E.M. Braga

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引用次数: 0

摘要

埃及伊蚊是登革热、黄热病、基孔肯雅热和寨卡病毒的媒介，是巴西和热带国家的主要公共卫生威胁；现在，它也在欧洲。茶树油（TTO）和姜黄素（Cur）对埃及伊蚊有杀幼虫和驱避作用。本研究以Pluronic F-68 （Plu）为原料，采用超临界CO2发泡法（SFM）制备多孔聚ε-己内酯（PCL）单体，以控制TTO和Cur的释放。通过改变SFM条件和单体组成来改变单体的性能。生物活性制剂在水和空气（重力法和风洞法）中的释放测试，挥发物持续15天以上。对埃及伊蚊种群进行了杀幼虫和驱蚊试验。本研究将toto -和toto - cu负载的PCL:Plu单体材料作为一种新型的、可持续的生物防蚊材料，具有杀虫和驱虫的双重作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Dual-Function Monoliths Prepared by Supercritical CO2 Foaming to Control Aedes aegypti

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Dual-Function Monoliths Prepared by Supercritical CO2 Foaming to Control Aedes aegypti

Aedes aegypti, a vector of dengue, yellow fever, chikungunya, and Zika, is a major public health threat in Brazil and tropical countries; now, it is also in Europe. Tea tree oil (TTO) and curcuminoids (Cur) have shown larvicidal and repellent effects against A. aegypti. This study developed porous poly(ε-caprolactone) (PCL) monoliths with Pluronic F-68 (Plu) using the supercritical CO₂ foaming method (SFM) for controlled TTO and Cur release. SFM conditions and monolith compositions were varied to modify monolith properties. Bioactive agents’ release was tested in water and air (gravimetric and wind tunnel) with volatiles persisting for over 15 days. Larvicidal and repellent tests were performed on A. aegypti colonies. This study prospects the TTO- and TTO-Cur-loaded PCL:Plu monoliths as emerging and sustainable biomaterials for mosquito control, acting as both larvicidal and insect repellents.

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来源期刊

ACS Sustainable Chemistry & Engineering CHEMISTRY, MULTIDISCIPLINARY-ENGINEERING, CHEMICAL

CiteScore

13.80

自引率

4.80%

发文量

1470

审稿时长

1.7 months

期刊介绍： ACS Sustainable Chemistry & Engineering is a prestigious weekly peer-reviewed scientific journal published by the American Chemical Society. Dedicated to advancing the principles of green chemistry and green engineering, it covers a wide array of research topics including green chemistry, green engineering, biomass, alternative energy, and life cycle assessment. The journal welcomes submissions in various formats, including Letters, Articles, Features, and Perspectives (Reviews), that address the challenges of sustainability in the chemical enterprise and contribute to the advancement of sustainable practices. Join us in shaping the future of sustainable chemistry and engineering.