TMEM138：从生物学功能到疾病。

IF 1.9 4区医学 Q3 PHYSIOLOGY

Physiological research Pub Date : 2025-04-30

Q Shi, L Zhu, L Zhang, Z Guo, Y Hao, Y Wang, J Gao, H Li, M Liu

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引用次数: 0

摘要

跨膜蛋白138 （TMEM138）是一种跨膜蛋白，属于跨膜蛋白超家族。最近的研究揭示了它参与多种生物过程，如细胞增殖、分化和凋亡。此外，TMEM138的异常表达与一系列疾病有关，特别是神经退行性疾病和肿瘤。本文综述了TMEM138的分子特征、生物学功能及其在疾病发病机制中的潜在作用。旨在为今后的研究和临床应用提供有价值的参考。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

TMEM138: From Biological Functions to Diseases.

Transmembrane Protein 138 (TMEM138) is a transmembrane protein belonging to the superfamily of transmembrane proteins. Recent research has unveiled its involvement in various biological processes such as cell proliferation, differentiation, and apoptosis. Furthermore, abnormal expression of TMEM138 has been linked to a range of diseases, particularly neurodege-nerative diseases and tumors. This review provides an overview of TMEM138, focusing on its molecular characteristics, biological functions, and potential roles in disease pathogenesis. The aim is to offer a valuable reference for future research and clinical applications.

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来源期刊

Physiological research 医学-生理学

CiteScore

4.00

自引率

4.80%

发文量

108

审稿时长

3 months

期刊介绍： Physiological Research is a peer reviewed Open Access journal that publishes articles on normal and pathological physiology, biochemistry, biophysics, and pharmacology. Authors can submit original, previously unpublished research articles, review articles, rapid or short communications. Instructions for Authors - Respect the instructions carefully when submitting your manuscript. Submitted manuscripts or revised manuscripts that do not follow these Instructions will not be included into the peer-review process. The articles are available in full versions as pdf files beginning with volume 40, 1991. The journal publishes the online Ahead of Print /Pre-Press version of the articles that are searchable in Medline and can be cited.