营养诱导的人类肝脏脂肪含量变化。

IF 1.9 4区医学 Q3 PHYSIOLOGY

Physiological research Pub Date : 2025-04-30

J Kovář, R Poledne

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引用次数: 0

摘要

代谢功能障碍相关的脂肪变性肝病（MASLD）影响了世界上大约30%的成年人，甚至导致心血管疾病死亡率的增加。饮食干预和运动是治疗MASLD患者最重要的工具。饮食成分对肝脏脂肪有深远的影响。本文综述了利用磁共振方法研究大量营养素对肝脏脂肪含量影响的研究结果。它侧重于干预研究，在长期饮食干预研究中操纵宏量营养素的含量和数量，更详细地说，是在几个小时内监测给药营养素对肝脏脂肪变化的影响的研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Nutrient-Induced Changes of Liver Fat Content in Humans.

Metabolic-dysfunction associated steatotic liver disease (MASLD) affects approximately 30 % of the world adult population and even contributes to the increased mortality from cardiovascular disease. Dietary intervention, along with exercise, is the most important tool for the treatment of MASLD patients. Dietary composition can have profound effects on liver fat. This review summarizes the results of studies that used MR methods to study the effect of macronutrients on liver fat content. It focuses on intervention studies manipulating the content and quantity of macronutrients in long-term dietary intervention studies and, in more detail, on studies monitoring the effect of administered nutrients on changes in liver fat over several hours.

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来源期刊

Physiological research 医学-生理学

CiteScore

4.00

自引率

4.80%

发文量

108

审稿时长

3 months

期刊介绍： Physiological Research is a peer reviewed Open Access journal that publishes articles on normal and pathological physiology, biochemistry, biophysics, and pharmacology. Authors can submit original, previously unpublished research articles, review articles, rapid or short communications. Instructions for Authors - Respect the instructions carefully when submitting your manuscript. Submitted manuscripts or revised manuscripts that do not follow these Instructions will not be included into the peer-review process. The articles are available in full versions as pdf files beginning with volume 40, 1991. The journal publishes the online Ahead of Print /Pre-Press version of the articles that are searchable in Medline and can be cited.