Linjie Wang, Lu Wang, Lin Jing, Yang Yang, Hui Miao, Xiaoya Liu, Dongzhi Suonanmu, Qingjia Ren, Fei Wang, Caolong Li
{"title":"基于溶剂主导信号放大策略的比例荧光/比色法/智能手机三模传感器用于果汁中褪黑素的精确快速检测。","authors":"Linjie Wang, Lu Wang, Lin Jing, Yang Yang, Hui Miao, Xiaoya Liu, Dongzhi Suonanmu, Qingjia Ren, Fei Wang, Caolong Li","doi":"10.1007/s00604-025-07248-0","DOIUrl":null,"url":null,"abstract":"<div><p>A ratio fluorescence/colorimetry/smartphone triple-mode sensor based on Ru-C<sub>3</sub>N<sub>4</sub> was established for precise and rapid detection of melatonin (MT). Specifically, Ru-C<sub>3</sub>N<sub>4</sub> with fine luminous characteristic and peroxidase-like activity catalyzes the oxidation of OPD to generate luminescent DAP which in turn suppresses intrinsic fluorescence of Ru-C<sub>3</sub>N<sub>4</sub> because of the fluorescence inner filter effect (IFE). MT can inhibit this catalytic process, leading to partial recovery of the fluorescence of Ru-C<sub>3</sub>N<sub>4</sub> and the decrease in UV–vis signal of the reaction system, as well as the gradual fading of the yellow color of the reaction solution. Hence, this triple-mode sensor can realize precise, reliable, and high-throughput determination of MT with correlative detection limits of 0.32, 0.46, and 0.67 μM. Moreover, this triple-mode sensor has been applied to MT detection in multiple juice samples with recoveries ranging from 86.00 to 99.68%, which indicates the suitability of the novel idea for the research and development of multimode optical sensors for food analysis.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 6","pages":""},"PeriodicalIF":5.3000,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A ratio fluorescence/colorimetry/smartphone triple-mode sensor based on solvent-dominated signal amplification strategy for precise and rapid detection of melatonin in fruit juice\",\"authors\":\"Linjie Wang, Lu Wang, Lin Jing, Yang Yang, Hui Miao, Xiaoya Liu, Dongzhi Suonanmu, Qingjia Ren, Fei Wang, Caolong Li\",\"doi\":\"10.1007/s00604-025-07248-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>A ratio fluorescence/colorimetry/smartphone triple-mode sensor based on Ru-C<sub>3</sub>N<sub>4</sub> was established for precise and rapid detection of melatonin (MT). Specifically, Ru-C<sub>3</sub>N<sub>4</sub> with fine luminous characteristic and peroxidase-like activity catalyzes the oxidation of OPD to generate luminescent DAP which in turn suppresses intrinsic fluorescence of Ru-C<sub>3</sub>N<sub>4</sub> because of the fluorescence inner filter effect (IFE). MT can inhibit this catalytic process, leading to partial recovery of the fluorescence of Ru-C<sub>3</sub>N<sub>4</sub> and the decrease in UV–vis signal of the reaction system, as well as the gradual fading of the yellow color of the reaction solution. Hence, this triple-mode sensor can realize precise, reliable, and high-throughput determination of MT with correlative detection limits of 0.32, 0.46, and 0.67 μM. Moreover, this triple-mode sensor has been applied to MT detection in multiple juice samples with recoveries ranging from 86.00 to 99.68%, which indicates the suitability of the novel idea for the research and development of multimode optical sensors for food analysis.</p><h3>Graphical Abstract</h3>\\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":705,\"journal\":{\"name\":\"Microchimica Acta\",\"volume\":\"192 6\",\"pages\":\"\"},\"PeriodicalIF\":5.3000,\"publicationDate\":\"2025-05-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microchimica Acta\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00604-025-07248-0\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchimica Acta","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s00604-025-07248-0","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
A ratio fluorescence/colorimetry/smartphone triple-mode sensor based on solvent-dominated signal amplification strategy for precise and rapid detection of melatonin in fruit juice
A ratio fluorescence/colorimetry/smartphone triple-mode sensor based on Ru-C3N4 was established for precise and rapid detection of melatonin (MT). Specifically, Ru-C3N4 with fine luminous characteristic and peroxidase-like activity catalyzes the oxidation of OPD to generate luminescent DAP which in turn suppresses intrinsic fluorescence of Ru-C3N4 because of the fluorescence inner filter effect (IFE). MT can inhibit this catalytic process, leading to partial recovery of the fluorescence of Ru-C3N4 and the decrease in UV–vis signal of the reaction system, as well as the gradual fading of the yellow color of the reaction solution. Hence, this triple-mode sensor can realize precise, reliable, and high-throughput determination of MT with correlative detection limits of 0.32, 0.46, and 0.67 μM. Moreover, this triple-mode sensor has been applied to MT detection in multiple juice samples with recoveries ranging from 86.00 to 99.68%, which indicates the suitability of the novel idea for the research and development of multimode optical sensors for food analysis.
期刊介绍：
As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.
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