Bibi Fatima, Farhan Raza Khan, Syeda Abeerah Tanveer
{"title":"根尖周围手术中贯通性骨缺损的愈合效果：系统回顾和荟萃分析。","authors":"Bibi Fatima, Farhan Raza Khan, Syeda Abeerah Tanveer","doi":"10.1111/aej.12951","DOIUrl":null,"url":null,"abstract":"<p><p>Through-and-through (TAT) cortical plate defects present a challenge in periapical surgery, influencing treatment outcomes. This study investigates whether guided regenerative procedures (GRPs) enhance cortical plate healing and overall success compared to non-GRP treatments in TAT lesions. A systematic search was conducted across PubMed, CINAHL Plus, Wiley Cochrane Library, and Dental and Oral Science. Studies assessing endodontically treated teeth with TAT lesions via Cone Beam Computed Tomography were included. The risk of bias was assessed using Cochrane Risk of Bias 2.0 tool and Newcastle-Ottawa Scale. Five studies met inclusion criteria, with four included in meta-analysis. No significant differences were observed in cortical plate healing (OR: 0.52, 95% CI: 0.12-2.39; p = 0.40) or treatment success (OR: 0.35, 95% CI: 0.09-1.39; p = 0.14) between GRPs and non-GRPs. Findings suggest that GRPs do not significantly improve healing in TAT lesions, highlighting the need for further studies with larger sample sizes.</p>","PeriodicalId":55581,"journal":{"name":"Australian Endodontic Journal","volume":" ","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Healing Outcomes of Through-And-Through Bone Defects in Periapical Surgery: A Systematic Review and Meta-Analysis.\",\"authors\":\"Bibi Fatima, Farhan Raza Khan, Syeda Abeerah Tanveer\",\"doi\":\"10.1111/aej.12951\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Through-and-through (TAT) cortical plate defects present a challenge in periapical surgery, influencing treatment outcomes. This study investigates whether guided regenerative procedures (GRPs) enhance cortical plate healing and overall success compared to non-GRP treatments in TAT lesions. A systematic search was conducted across PubMed, CINAHL Plus, Wiley Cochrane Library, and Dental and Oral Science. Studies assessing endodontically treated teeth with TAT lesions via Cone Beam Computed Tomography were included. The risk of bias was assessed using Cochrane Risk of Bias 2.0 tool and Newcastle-Ottawa Scale. Five studies met inclusion criteria, with four included in meta-analysis. No significant differences were observed in cortical plate healing (OR: 0.52, 95% CI: 0.12-2.39; p = 0.40) or treatment success (OR: 0.35, 95% CI: 0.09-1.39; p = 0.14) between GRPs and non-GRPs. Findings suggest that GRPs do not significantly improve healing in TAT lesions, highlighting the need for further studies with larger sample sizes.</p>\",\"PeriodicalId\":55581,\"journal\":{\"name\":\"Australian Endodontic Journal\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-05-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Australian Endodontic Journal\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/aej.12951\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Australian Endodontic Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/aej.12951","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Healing Outcomes of Through-And-Through Bone Defects in Periapical Surgery: A Systematic Review and Meta-Analysis.
Through-and-through (TAT) cortical plate defects present a challenge in periapical surgery, influencing treatment outcomes. This study investigates whether guided regenerative procedures (GRPs) enhance cortical plate healing and overall success compared to non-GRP treatments in TAT lesions. A systematic search was conducted across PubMed, CINAHL Plus, Wiley Cochrane Library, and Dental and Oral Science. Studies assessing endodontically treated teeth with TAT lesions via Cone Beam Computed Tomography were included. The risk of bias was assessed using Cochrane Risk of Bias 2.0 tool and Newcastle-Ottawa Scale. Five studies met inclusion criteria, with four included in meta-analysis. No significant differences were observed in cortical plate healing (OR: 0.52, 95% CI: 0.12-2.39; p = 0.40) or treatment success (OR: 0.35, 95% CI: 0.09-1.39; p = 0.14) between GRPs and non-GRPs. Findings suggest that GRPs do not significantly improve healing in TAT lesions, highlighting the need for further studies with larger sample sizes.
期刊介绍：
The Australian Endodontic Journal provides a forum for communication in the different fields that encompass endodontics for all specialists and dentists with an interest in the morphology, physiology, and pathology of the human tooth, in particular the dental pulp, root and peri-radicular tissues.
The Journal features regular clinical updates, research reports and case reports from authors worldwide, and also publishes meeting abstracts, society news and historical endodontic glimpses.
The Australian Endodontic Journal is a publication for dentists in general and specialist practice devoted solely to endodontics. It aims to promote communication in the different fields that encompass endodontics for those dentists who have a special interest in endodontics.
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