Aisha A Almulla, Hanna Augustin, Luai A Ahmed, Linnea Bärebring
{"title":"超加工食品摄入、饮食质量和妊娠期糖尿病风险:来自Mutaba'ah研究的横断面分析","authors":"Aisha A Almulla, Hanna Augustin, Luai A Ahmed, Linnea Bärebring","doi":"10.1186/s12986-025-00950-z","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>High intake of Ultra-Processed Foods (UPF) has raised concerns about how they might impact maternal diet and potentially increase the risk of Gestational Diabetes Mellitus (GDM). This study aimed to evaluate the associations between UPF intake or adherence to the Mediterranean Diet and GDM among pregnant women in the United Arab Emirates.</p><p><strong>Methods: </strong>Pregnant women (n = 1054) from the dietary subcohort within the prospective Mutaba'ah Study cohort were included. Diet was assessed through a semi-quantitative food frequency questionnaire, and UPF intake in servings/day was classified according to the NOVA system. The alternate Mediterranean Diet (aMED) score specific for pregnancy defined adherence to the Mediterranean Diet. GDM diagnosis was based on the National Institute for Health and Clinical Excellence criteria. Logistic regression models adjusted for maternal age, first trimester body mass index, parity, gestational age, education level, employment status, physical activity, and husband's smoking status were used to assess associations between UPF intake or aMED score and GDM.</p><p><strong>Results: </strong>Mean ± SD UPF intake was 9.4 ± 3.4 servings/day and mean aMED score was 4.0 ± 1.5. Women in the highest tertile of UPF intake had lower aMED score than those in the lowest tertile (4.3 ± 1.4 vs. 3.6 ± 1.4, P < 0.001). Women in the highest tertile of UPF intake had higher intakes of carbohydrates, saturated fatty acids, sodium, and selenium than those in the lowest tertile, while intakes of protein, total fat, monounsaturated fatty acids, and most micronutrients were lower (P < 0.05). Neither tertiles of UPF intake (third tertile compared to the lowest OR = 0.85, 95% CI: 0.54-1.34) nor continuous UPF intake (OR = 0.97, 95% CI: 0.92-1.03) was associated with GDM. Similarly, aMED score was not associated with GDM in either tertile of the score (third tertile compared to the lowest OR = 0.94, 95% CI: 0.54-1.64) or as a continuous variable (OR = 0.99, 95% CI: 0.87-1.11).</p><p><strong>Conclusions: </strong>Higher intake of UPF was associated with a lower adherence to the Mediterranean Diet. However, neither UPF intake nor aMED score was associated with GDM.</p>","PeriodicalId":19196,"journal":{"name":"Nutrition & Metabolism","volume":"22 1","pages":"53"},"PeriodicalIF":3.9000,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105120/pdf/","citationCount":"0","resultStr":"{\"title\":\"Ultra-processed food intake, diet quality, and risk of gestational diabetes mellitus: a cross-sectional analysis from the Mutaba'ah study.\",\"authors\":\"Aisha A Almulla, Hanna Augustin, Luai A Ahmed, Linnea Bärebring\",\"doi\":\"10.1186/s12986-025-00950-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>High intake of Ultra-Processed Foods (UPF) has raised concerns about how they might impact maternal diet and potentially increase the risk of Gestational Diabetes Mellitus (GDM). This study aimed to evaluate the associations between UPF intake or adherence to the Mediterranean Diet and GDM among pregnant women in the United Arab Emirates.</p><p><strong>Methods: </strong>Pregnant women (n = 1054) from the dietary subcohort within the prospective Mutaba'ah Study cohort were included. Diet was assessed through a semi-quantitative food frequency questionnaire, and UPF intake in servings/day was classified according to the NOVA system. The alternate Mediterranean Diet (aMED) score specific for pregnancy defined adherence to the Mediterranean Diet. GDM diagnosis was based on the National Institute for Health and Clinical Excellence criteria. Logistic regression models adjusted for maternal age, first trimester body mass index, parity, gestational age, education level, employment status, physical activity, and husband's smoking status were used to assess associations between UPF intake or aMED score and GDM.</p><p><strong>Results: </strong>Mean ± SD UPF intake was 9.4 ± 3.4 servings/day and mean aMED score was 4.0 ± 1.5. Women in the highest tertile of UPF intake had lower aMED score than those in the lowest tertile (4.3 ± 1.4 vs. 3.6 ± 1.4, P < 0.001). Women in the highest tertile of UPF intake had higher intakes of carbohydrates, saturated fatty acids, sodium, and selenium than those in the lowest tertile, while intakes of protein, total fat, monounsaturated fatty acids, and most micronutrients were lower (P < 0.05). Neither tertiles of UPF intake (third tertile compared to the lowest OR = 0.85, 95% CI: 0.54-1.34) nor continuous UPF intake (OR = 0.97, 95% CI: 0.92-1.03) was associated with GDM. Similarly, aMED score was not associated with GDM in either tertile of the score (third tertile compared to the lowest OR = 0.94, 95% CI: 0.54-1.64) or as a continuous variable (OR = 0.99, 95% CI: 0.87-1.11).</p><p><strong>Conclusions: </strong>Higher intake of UPF was associated with a lower adherence to the Mediterranean Diet. 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Ultra-processed food intake, diet quality, and risk of gestational diabetes mellitus: a cross-sectional analysis from the Mutaba'ah study.
Background: High intake of Ultra-Processed Foods (UPF) has raised concerns about how they might impact maternal diet and potentially increase the risk of Gestational Diabetes Mellitus (GDM). This study aimed to evaluate the associations between UPF intake or adherence to the Mediterranean Diet and GDM among pregnant women in the United Arab Emirates.
Methods: Pregnant women (n = 1054) from the dietary subcohort within the prospective Mutaba'ah Study cohort were included. Diet was assessed through a semi-quantitative food frequency questionnaire, and UPF intake in servings/day was classified according to the NOVA system. The alternate Mediterranean Diet (aMED) score specific for pregnancy defined adherence to the Mediterranean Diet. GDM diagnosis was based on the National Institute for Health and Clinical Excellence criteria. Logistic regression models adjusted for maternal age, first trimester body mass index, parity, gestational age, education level, employment status, physical activity, and husband's smoking status were used to assess associations between UPF intake or aMED score and GDM.
Results: Mean ± SD UPF intake was 9.4 ± 3.4 servings/day and mean aMED score was 4.0 ± 1.5. Women in the highest tertile of UPF intake had lower aMED score than those in the lowest tertile (4.3 ± 1.4 vs. 3.6 ± 1.4, P < 0.001). Women in the highest tertile of UPF intake had higher intakes of carbohydrates, saturated fatty acids, sodium, and selenium than those in the lowest tertile, while intakes of protein, total fat, monounsaturated fatty acids, and most micronutrients were lower (P < 0.05). Neither tertiles of UPF intake (third tertile compared to the lowest OR = 0.85, 95% CI: 0.54-1.34) nor continuous UPF intake (OR = 0.97, 95% CI: 0.92-1.03) was associated with GDM. Similarly, aMED score was not associated with GDM in either tertile of the score (third tertile compared to the lowest OR = 0.94, 95% CI: 0.54-1.64) or as a continuous variable (OR = 0.99, 95% CI: 0.87-1.11).
Conclusions: Higher intake of UPF was associated with a lower adherence to the Mediterranean Diet. However, neither UPF intake nor aMED score was associated with GDM.
期刊介绍:
Nutrition & Metabolism publishes studies with a clear focus on nutrition and metabolism with applications ranging from nutrition needs, exercise physiology, clinical and population studies, as well as the underlying mechanisms in these aspects.
The areas of interest for Nutrition & Metabolism encompass studies in molecular nutrition in the context of obesity, diabetes, lipedemias, metabolic syndrome and exercise physiology. Manuscripts related to molecular, cellular and human metabolism, nutrient sensing and nutrient–gene interactions are also in interest, as are submissions that have employed new and innovative strategies like metabolomics/lipidomics or other omic-based biomarkers to predict nutritional status and metabolic diseases.
Key areas we wish to encourage submissions from include:
-how diet and specific nutrients interact with genes, proteins or metabolites to influence metabolic phenotypes and disease outcomes;
-the role of epigenetic factors and the microbiome in the pathogenesis of metabolic diseases and their influence on metabolic responses to diet and food components;
-how diet and other environmental factors affect epigenetics and microbiota; the extent to which genetic and nongenetic factors modify personal metabolic responses to diet and food compositions and the mechanisms involved;
-how specific biologic networks and nutrient sensing mechanisms attribute to metabolic variability.