尼日利亚西南部年轻成人镰状细胞性贫血血液学指标的参考区间

IF 1.6 Q2 MULTIDISCIPLINARY SCIENCES

BMC Research Notes Pub Date : 2025-05-26 DOI:10.1186/s13104-025-07303-2

Muritala A Asafa, Ibrahim O Ahmed, Mary B Agim, Taofik A Fabinu, Simeon O Kusoro, Blessing T Ogunoye, Oluwadare Ogunlade, Rahman A Bolarinwa

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引用次数: 0

摘要

目的：参考区间（RIs）对结果的解释和患者的整体管理至关重要。目前，尼日利亚镰状细胞贫血（SCA）患者的血液学参数没有已知的既定参考值，这使得临床医生难以适当解释和诊断异常。本研究旨在建立SCA患者某些血液学指标的RIs。结果：一般情况下，红细胞压积（%）的参考区间为17.8 ~ 29.7，白细胞（x 109/l）在5.9 ~ 12.1之间，血小板计数（x 109/l）在166 ~ 465之间。对于男性参与者，红细胞压积（%）的参考区间在17.8至29之间，白细胞（x 109/l）介于6.7至12.1之间，血小板计数（x 109/l）介于166至399之间。女性红细胞压积（%）在18.7 ~ 28.5之间，白细胞（WBC）在5.9 ~ 13.0 × 109/l之间，血小板（x 109/l）在225 ~ 465之间。

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Reference intervals of haematological indices for young adults with sickle cell anaemia in Southwestern Nigeria.

Objective: Reference intervals (RIs) are crucial for the interpretation of results and overall patient management. There are currently no known established reference values for haematological parameters for patients with sickle cell anaemia (SCA) in Nigeria, making it difficult for clinicians to interpret and diagnose abnormalities appropriately. This study aimed at establishing RIs of some haematological indices for individuals with SCA.

Results: Generally, the reference interval for Haematocrit (%) is 17.8 to 29.7, while the WBC (x 10⁹/l) ranged between 5.9 and 12.1 and the platelet count (x 10⁹/l) is 166-465. For the male participants, the reference interval for haematocrit (%) was found to be between 17.8 and 29, the WBC (x 10⁹/l) ranged between 6.7 and 12.1 and the platelet count (x 10⁹/l) was between 166 and 399. The female subjects had a haematocrit (%) of between 18.7 and 28.5, WBC of between 5.9 10⁹/l and 13.0 × 10⁹/l and the platelet count (x 10⁹/l) was between 225 and 465.

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来源期刊

BMC Research Notes Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)

CiteScore

3.60

自引率

0.00%

发文量

363

审稿时长

15 weeks

期刊介绍： BMC Research Notes publishes scientifically valid research outputs that cannot be considered as full research or methodology articles. We support the research community across all scientific and clinical disciplines by providing an open access forum for sharing data and useful information; this includes, but is not limited to, updates to previous work, additions to established methods, short publications, null results, research proposals and data management plans.