Olivier Iryivuze, Anthony Ayotunde Olasinde, Alain Favina, Joshua Muhumuza, Anyanwu Godson Emeka, Ahmed Kiswezi
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This study aimed to determine the incidence of ACS in tibia fractures and its predictors in Uganda.</p><p><strong>Methods: </strong>A prospective cohort study was conducted for 6 months at three tertiary hospitals in Uganda where patients with tibia fractures were examined clinically and had their intracompartmental pressure (ICP) measured for ACS using the Whitesides technique, with a 24-hour follow-up after admission and after orthopaedic treatment. All patients were managed as per the ATLS protocol; Data were analyzed using SPSS version 22.</p><p><strong>Results: </strong>The study enrolled 130 study participants with tibia fracture. The majority of participants were males (76.9%). The age group of 18-30 years made up 55.4%. The incidence of ACS was found to be 8.5% (11/130). Among the 11 people with ACS, all had both tibia and fibula fractures, and 8/11 had closed fractures. Smoking (aRR = 2.189, CI = 1.614-7.812, P = 0.049) and swelling of the injured limb (aRR = 3.793, CI = 1.479-9.727, P = 0.008) were the independent predictors of ACS.</p><p><strong>Conclusion: </strong>The incidence of ACS in Uganda was 8.5%. 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引用次数: 0
摘要
简介：急性筋膜室综合征（ACS）是一种破坏性和时间敏感的紧急情况，每年增加肢体残疾，截肢和死亡。然而，关于乌干达胫骨骨折中ACS的发生率及其预测因素的数据缺乏，这可以帮助我们挽救肢体。本研究旨在确定乌干达胫骨骨折中ACS的发生率及其预测因素。方法：在乌干达三所三级医院进行为期6个月的前瞻性队列研究，对胫骨骨折患者进行临床检查，并使用Whitesides技术测量ACS的腔内压（ICP），并在入院后和骨科治疗后进行24小时随访。所有患者均按照ATLS方案进行管理；数据分析采用SPSS version 22。结果：该研究招募了130名胫骨骨折患者。大多数参与者为男性（76.9%）。18-30岁年龄组占55.4%。ACS的发生率为8.5%（11/130）。11例ACS患者均有胫腓骨骨折，8/11为闭合性骨折。吸烟（aRR = 2.189, CI = 1.614 ~ 7.812, P = 0.049）和肢体肿胀（aRR = 3.793, CI = 1.479 ~ 9.727, P = 0.008）是ACS的独立预测因素。结论：乌干达ACS的发病率为8.5%。有吸烟史和肢体肿胀临床症状的人应更密切监测。临床试验号：不适用。
Acute compartment syndrome and its predictors among patients with tibia fracture in Uganda: a multicenter prospective cohort study.
Introduction: Acute compartment syndrome (ACS) is a devastating and time-sensitive emergency that increases limb disabilities, amputations, and deaths annually. However, there is a paucity of data on the incidence of ACS in tibia fractures and its predictors in Uganda that can help us save the limb. This study aimed to determine the incidence of ACS in tibia fractures and its predictors in Uganda.
Methods: A prospective cohort study was conducted for 6 months at three tertiary hospitals in Uganda where patients with tibia fractures were examined clinically and had their intracompartmental pressure (ICP) measured for ACS using the Whitesides technique, with a 24-hour follow-up after admission and after orthopaedic treatment. All patients were managed as per the ATLS protocol; Data were analyzed using SPSS version 22.
Results: The study enrolled 130 study participants with tibia fracture. The majority of participants were males (76.9%). The age group of 18-30 years made up 55.4%. The incidence of ACS was found to be 8.5% (11/130). Among the 11 people with ACS, all had both tibia and fibula fractures, and 8/11 had closed fractures. Smoking (aRR = 2.189, CI = 1.614-7.812, P = 0.049) and swelling of the injured limb (aRR = 3.793, CI = 1.479-9.727, P = 0.008) were the independent predictors of ACS.
Conclusion: The incidence of ACS in Uganda was 8.5%. People with a history of cigarette smoking and clinical symptoms of swelling of the limb should be monitored more closely.
期刊介绍：
BMC Musculoskeletal Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of musculoskeletal disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
The scope of the Journal covers research into rheumatic diseases where the primary focus relates specifically to a component(s) of the musculoskeletal system.
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