3D打印过程中挤压压力对3D打印样品中人支气管上皮细胞活力的影响

IF 3.4 3区医学 Q1 ENGINEERING, MULTIDISCIPLINARY

Biomimetics Pub Date : 2025-05-08 DOI:10.3390/biomimetics10050297

Taieba Tuba Rahman, Nathan Wood, Zhijian Pei, Hongmin Qin, Padmini Mohan

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引用次数: 0

摘要

本研究探讨了3D打印过程中不同水平的挤压压力如何影响打印样品中嵌入的人支气管上皮细胞（HBE）的细胞活力。在本研究中，样品在三个水平的挤压压力下打印。显微成像通过活/死染色评估细胞活力。结果表明，挤压压力从50 kPa增加到100 kPa，细胞死亡程度越高。这些结果证明了挤压压力如何影响HBE细胞的活力，并为进一步研究呼吸组织中压力诱导的反应提供了基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Effects of Extrusion Pressure During 3D Printing on Viability of Human Bronchial Epithelial Cells in 3D Printed Samples.

This study investigates how different levels of extrusion pressure during 3D printing affect the cell viability of human bronchial epithelial (HBE) cells embedded in printed samples. In this study, samples were printed at three levels of extrusion pressure. The cell viability was assessed through live/dead staining via microscopic imaging. The results show that increasing the extrusion pressure from 50 to 100 kPa led to a higher degree of cell death. These results demonstrate how the extrusion pressure affects the viability of HBE cells and provide a basis for future studies on pressure-induced responses in respiratory tissues.

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