pd催化串联Suzuki偶联/Heck环化反应合成含双芴基的双环芳烃。

IF 3.9 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemistry - A European Journal Pub Date : 2025-05-27 DOI:10.1002/chem.202501516

Luna Yang, Wangxuan Li, Shijie Gao, Hongchi Zhao, Yonggang Wu

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引用次数: 0

摘要

采用钯催化的铃木偶联/Heck环化串联反应，在一锅内制备了多种双芴基双环芳烃（BAEs）及其衍生物。在新方案中，选择2-溴苯基三氟甲烷磺酸盐及其类似衍生物作为反应底物之一，与合适的芳基硼酸酯底物进行铃木偶联/Heck环化串联反应，得到预期的BAEs及其衍生物。在新设计的方案中，原料更容易获得，可用于合成更多的BAEs及其衍生物。

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Synthesis of Bistricyclic Aromatic Enes Containing Bifluorenylidene Units via Pd-Catalyzed Tandem Suzuki Coupling/Heck Cyclization Reaction.

A variety of bifluorenylidene-based bistricyclic aromatic enes (BAEs) and their derivatives have been prepared via the palladium-catalyzed Suzuki coupling/Heck cyclization tandem reaction in one pot. In the new scheme 2-bromophenyl trifluoromethanesulfonate and similar derivatives were chosen as one of reaction substrates, which could undergo tandem Suzuki coupling/Heck cyclization reaction with suitable arylboronic acid ester substrates to afford the expected BAEs and their derivatives. In the newly designed scheme, the raw materials are easier to obtain and can be applied to the synthesis of more BAEs and their derivatives.

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来源期刊

Chemistry - A European Journal 化学-化学综合

CiteScore

7.90

自引率

4.70%

发文量

1808

审稿时长

1.8 months

期刊介绍： Chemistry—A European Journal is a truly international journal with top quality contributions (2018 ISI Impact Factor: 5.16). It publishes a wide range of outstanding Reviews, Minireviews, Concepts, Full Papers, and Communications from all areas of chemistry and related fields. Based in Europe Chemistry—A European Journal provides an excellent platform for increasing the visibility of European chemistry as well as for featuring the best research from authors from around the world. All manuscripts are peer-reviewed, and electronic processing ensures accurate reproduction of text and data, plus short publication times. The Concepts section provides nonspecialist readers with a useful conceptual guide to unfamiliar areas and experts with new angles on familiar problems. Chemistry—A European Journal is published on behalf of ChemPubSoc Europe, a group of 16 national chemical societies from within Europe, and supported by the Asian Chemical Editorial Societies. The ChemPubSoc Europe family comprises: Angewandte Chemie, Chemistry—A European Journal, European Journal of Organic Chemistry, European Journal of Inorganic Chemistry, ChemPhysChem, ChemBioChem, ChemMedChem, ChemCatChem, ChemSusChem, ChemPlusChem, ChemElectroChem, and ChemistryOpen.