以患者为中心的肿瘤和种系遗传结果的整合可以改善癌症治疗

IF 58.7 1区医学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Nature Medicine Pub Date : 2025-05-27 DOI:10.1038/s41591-025-03686-8

Alanna J. Church, Oindrila Bhattacharyya, Julie O. Culver, Yonatan Amzaleg, Erin Linnenbringer, Maeve Smart, Christina Ip-Toma, Adan Reinosa Rivera, Bethany Davis, Charité Ricker, Heinz-Josef Lenz, Stacy W. Gray, Heather Hampel, David W. Craig

引用次数: 0

摘要

生殖系测序应与癌症的体细胞检测相结合，以提供疾病的全面遗传评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Patient-centered integration of tumor and germline genetic results can improve cancer care

查看原文本刊更多论文

Patient-centered integration of tumor and germline genetic results can improve cancer care

Germline sequencing should be integrated with somatic testing of cancers to provide a comprehensive genetic assessment of disease.

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来源期刊

Nature Medicine 医学-生化与分子生物学

CiteScore

100.90

自引率

0.70%

发文量

525

审稿时长

1 months

期刊介绍： Nature Medicine is a monthly journal publishing original peer-reviewed research in all areas of medicine. The publication focuses on originality, timeliness, interdisciplinary interest, and the impact on improving human health. In addition to research articles, Nature Medicine also publishes commissioned content such as News, Reviews, and Perspectives. This content aims to provide context for the latest advances in translational and clinical research, reaching a wide audience of M.D. and Ph.D. readers. All editorial decisions for the journal are made by a team of full-time professional editors. Nature Medicine consider all types of clinical research, including: -Case-reports and small case series -Clinical trials, whether phase 1, 2, 3 or 4 -Observational studies -Meta-analyses -Biomarker studies -Public and global health studies Nature Medicine is also committed to facilitating communication between translational and clinical researchers. As such, we consider “hybrid” studies with preclinical and translational findings reported alongside data from clinical studies.