Advancing Drug Stability Using Non-Aqueous Gels: Properties, Applications, and Emerging Challenges.

This study explores the emerging potential of non-aqueous gels for topical therapy, examining their unique properties, diverse applications, and the challenges involved in their formulation and clinical use. By highlighting these aspects, the article aims to shed light on the future of localized drug delivery and inspire further research and innovation in this promising field. Additionally, the article addresses the critical need for regulatory considerations, stability testing, and patient acceptability. It also emphasizes the role of non-aqueous gels in revolutionizing dermatological and transdermal therapies, particularly by enhancing the stability of drugs that are hydrolyzed in the presence of water.