{"title":"显微镜下多血管炎患者输注利妥昔单抗后严重低钾血症性麻痹。","authors":"Yousuf Sherwani, Ayham Alsaab, Mohan Sengodan","doi":"10.7759/cureus.84750","DOIUrl":null,"url":null,"abstract":"<p><p>Rituximab is an anti-CD20 monoclonal antibody that has become an increasingly popular choice for the treatment of various autoimmune diseases. Various adverse effects have been attributed to the use of rituximab. Hypokalemia is one rare adverse reaction that is under reported in the literature and is life threatening. Here we report the case of a patient with symptomatic hypokalemia after IV rituximab infusion. Acute hypokalemia should be taken into account by healthcare professionals as a possible side effect after rituximab infusion.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 5","pages":"e84750"},"PeriodicalIF":1.0000,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103242/pdf/","citationCount":"0","resultStr":"{\"title\":\"Severe Hypokalemic Paralysis Following Rituximab Infusion in a Patient With Microscopic Polyangitis.\",\"authors\":\"Yousuf Sherwani, Ayham Alsaab, Mohan Sengodan\",\"doi\":\"10.7759/cureus.84750\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Rituximab is an anti-CD20 monoclonal antibody that has become an increasingly popular choice for the treatment of various autoimmune diseases. Various adverse effects have been attributed to the use of rituximab. Hypokalemia is one rare adverse reaction that is under reported in the literature and is life threatening. Here we report the case of a patient with symptomatic hypokalemia after IV rituximab infusion. Acute hypokalemia should be taken into account by healthcare professionals as a possible side effect after rituximab infusion.</p>\",\"PeriodicalId\":93960,\"journal\":{\"name\":\"Cureus\",\"volume\":\"17 5\",\"pages\":\"e84750\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-05-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103242/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cureus\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7759/cureus.84750\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/5/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cureus","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7759/cureus.84750","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Severe Hypokalemic Paralysis Following Rituximab Infusion in a Patient With Microscopic Polyangitis.
Rituximab is an anti-CD20 monoclonal antibody that has become an increasingly popular choice for the treatment of various autoimmune diseases. Various adverse effects have been attributed to the use of rituximab. Hypokalemia is one rare adverse reaction that is under reported in the literature and is life threatening. Here we report the case of a patient with symptomatic hypokalemia after IV rituximab infusion. Acute hypokalemia should be taken into account by healthcare professionals as a possible side effect after rituximab infusion.