{"title":"[格伦手术后络的处理及其对单心室患者的影响:一项单中心研究]。","authors":"Yasmin Abdelrazek Ali, Nehad El-Sayed Nour El-Deen, Ghada Samir Elshahed","doi":"10.24875/RECIC.M24000475","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction and objectives: </strong>The bidirectional Glenn shunt (BDG) is an essential step in the repair of a physiologically single-ventricle heart. BDG increases pulmonary blood flow, allows growth of the pulmonary arteries, and improves SaO<sub>2</sub>. The procedure also allows unloading of ventricular volume, thereby improving survival. Our aim was to register all patients who developed collaterals following BDG, document the management methods used, and assess their impact.</p><p><strong>Methods: </strong>We included 56 patients who underwent BDG procedures at a median age of 2.08 (1-3) years. After BDG, peripheral pulmonary stenting was used in 2 patients. Symptomatic hyperviscosity was present in 10 patients (17.86%), who underwent venesection. BDG was unsuccessful in 2 patients. Venovenous collaterals were observed in 41 patients (73.2%), and aortopulmonary collaterals in 37 (66.1%).</p><p><strong>Results: </strong>Hematocrit levels were significantly higher in patients with venovenous collaterals (50.00 ± 8.76) than in those without (<i>P</i> = .031). Mean pulmonary artery pressure was also significantly higher in patients with venovenous collaterals (15 [12-18] mmHg; <i>P</i> = .025). One patient had undergone successful closure of venovenous collaterals to epicardial veins and abdominal veins 3 years previously. Seven patients underwent transcatheter closure (TCC) of collaterals. Of these, 4 patients underwent TCC of venovenous collaterals to left and right pulmonary veins; 1 patient underwent closure of an aortopulmonary collateral; 1 patient underwent a failed attempt at venovenous collateral closure that was complicated by an ischemic stroke; and 1 patient had localized extravasation upon separation of the cable. A highly statistically significant increase in SaO<sub>2</sub> was observed after TCC of venovenous collaterals (69.83 ± 10.91 vs 82.83 ± 9.87; <i>P</i> = .008).</p><p><strong>Conclusions: </strong>TCC of collaterals is a technically demanding but effective management strategy following BDG to improve patients' SaO<sub>2</sub> and quality of life. Awareness of possible complications and their effective management is crucial.</p>","PeriodicalId":34295,"journal":{"name":"REC Interventional Cardiology","volume":"6 4","pages":"296-304"},"PeriodicalIF":1.1000,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12097323/pdf/","citationCount":"0","resultStr":"{\"title\":\"[Management of collaterals after Glenn procedure and its impact on patients with a single ventricle: a single-center study].\",\"authors\":\"Yasmin Abdelrazek Ali, Nehad El-Sayed Nour El-Deen, Ghada Samir Elshahed\",\"doi\":\"10.24875/RECIC.M24000475\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction and objectives: </strong>The bidirectional Glenn shunt (BDG) is an essential step in the repair of a physiologically single-ventricle heart. BDG increases pulmonary blood flow, allows growth of the pulmonary arteries, and improves SaO<sub>2</sub>. The procedure also allows unloading of ventricular volume, thereby improving survival. Our aim was to register all patients who developed collaterals following BDG, document the management methods used, and assess their impact.</p><p><strong>Methods: </strong>We included 56 patients who underwent BDG procedures at a median age of 2.08 (1-3) years. After BDG, peripheral pulmonary stenting was used in 2 patients. Symptomatic hyperviscosity was present in 10 patients (17.86%), who underwent venesection. BDG was unsuccessful in 2 patients. Venovenous collaterals were observed in 41 patients (73.2%), and aortopulmonary collaterals in 37 (66.1%).</p><p><strong>Results: </strong>Hematocrit levels were significantly higher in patients with venovenous collaterals (50.00 ± 8.76) than in those without (<i>P</i> = .031). Mean pulmonary artery pressure was also significantly higher in patients with venovenous collaterals (15 [12-18] mmHg; <i>P</i> = .025). One patient had undergone successful closure of venovenous collaterals to epicardial veins and abdominal veins 3 years previously. Seven patients underwent transcatheter closure (TCC) of collaterals. Of these, 4 patients underwent TCC of venovenous collaterals to left and right pulmonary veins; 1 patient underwent closure of an aortopulmonary collateral; 1 patient underwent a failed attempt at venovenous collateral closure that was complicated by an ischemic stroke; and 1 patient had localized extravasation upon separation of the cable. A highly statistically significant increase in SaO<sub>2</sub> was observed after TCC of venovenous collaterals (69.83 ± 10.91 vs 82.83 ± 9.87; <i>P</i> = .008).</p><p><strong>Conclusions: </strong>TCC of collaterals is a technically demanding but effective management strategy following BDG to improve patients' SaO<sub>2</sub> and quality of life. 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引用次数: 0
摘要
简介和目的:双向格伦分流术(BDG)是修复生理性单心室心脏的重要步骤。BDG增加肺血流量,促进肺动脉生长,改善SaO2。该手术还可以减少心室容积,从而提高生存率。我们的目的是登记所有在BDG后出现侧枝的患者,记录所使用的管理方法,并评估其影响。方法:我们纳入56例接受BDG手术的患者,中位年龄为2.08(1-3)岁。2例患者行肺外周支架置入术。10例患者(17.86%)行静脉切除术后出现症状性高粘稠度。2例患者BDG治疗失败。41例(73.2%)观察到静脉侧支,37例(66.1%)观察到主动脉肺侧支。结果:有静脉侧支的患者红细胞压积水平(50.00±8.76)明显高于无静脉侧支的患者(P = 0.031)。静脉侧支患者的平均肺动脉压也显著升高(15 [12-18]mmHg;P = .025)。1例患者3年前成功闭合心外膜静脉和腹腔静脉的静脉侧支。7例患者行经导管络闭合术。其中,4例患者行左、右肺静脉静脉侧支TCC;1例患者行主动脉肺动脉侧支闭合术;1例患者接受静脉静脉侧枝闭合失败,并发缺血性中风;1例患者分离后出现局部外渗。静脉-静脉侧支TCC术后SaO2升高具有高度统计学意义(69.83±10.91 vs 82.83±9.87;P = .008)。结论:经络切除是一种技术要求高但有效的治疗策略,可改善BDG患者的SaO2和生活质量。意识到可能的并发症及其有效的管理是至关重要的。
[Management of collaterals after Glenn procedure and its impact on patients with a single ventricle: a single-center study].
Introduction and objectives: The bidirectional Glenn shunt (BDG) is an essential step in the repair of a physiologically single-ventricle heart. BDG increases pulmonary blood flow, allows growth of the pulmonary arteries, and improves SaO2. The procedure also allows unloading of ventricular volume, thereby improving survival. Our aim was to register all patients who developed collaterals following BDG, document the management methods used, and assess their impact.
Methods: We included 56 patients who underwent BDG procedures at a median age of 2.08 (1-3) years. After BDG, peripheral pulmonary stenting was used in 2 patients. Symptomatic hyperviscosity was present in 10 patients (17.86%), who underwent venesection. BDG was unsuccessful in 2 patients. Venovenous collaterals were observed in 41 patients (73.2%), and aortopulmonary collaterals in 37 (66.1%).
Results: Hematocrit levels were significantly higher in patients with venovenous collaterals (50.00 ± 8.76) than in those without (P = .031). Mean pulmonary artery pressure was also significantly higher in patients with venovenous collaterals (15 [12-18] mmHg; P = .025). One patient had undergone successful closure of venovenous collaterals to epicardial veins and abdominal veins 3 years previously. Seven patients underwent transcatheter closure (TCC) of collaterals. Of these, 4 patients underwent TCC of venovenous collaterals to left and right pulmonary veins; 1 patient underwent closure of an aortopulmonary collateral; 1 patient underwent a failed attempt at venovenous collateral closure that was complicated by an ischemic stroke; and 1 patient had localized extravasation upon separation of the cable. A highly statistically significant increase in SaO2 was observed after TCC of venovenous collaterals (69.83 ± 10.91 vs 82.83 ± 9.87; P = .008).
Conclusions: TCC of collaterals is a technically demanding but effective management strategy following BDG to improve patients' SaO2 and quality of life. Awareness of possible complications and their effective management is crucial.