[神经发育:跨门诊学的维度]。

IF 0.4 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
M S-medecine Sciences Pub Date : 2025-05-01 Epub Date: 2025-05-26 DOI:10.1051/medsci/2025071
Anton Iftimovici, Renaud Jardri, Aline Lefebvre, Jasmina Mallet, Antoine Lefrere
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引用次数: 0

摘要

神经发育维度是未来精准精神病学面临的主要挑战。它提供了一个跨诊断框架,允许在传统诊断类别之外重新定义精神疾病,如自闭症谱系障碍、注意力缺陷/多动障碍、精神分裂症和双相情感障碍。这个模型是基于识别在脆弱的关键时期大脑发育轨迹的偏差。该框架采用整合临床、生物学、神经影像学和神经生理学数据的多模式方法,旨在定义个性化的神经发育负担,为分层和针对每个发育特征量身定制的个性化治疗开辟新的前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Neurodevelopment: a transnosographic dimension].

The neurodevelopmental dimension represents a major challenge for the future of precision psychiatry. It provides a transdiagnostic framework, that allows for the redefinition of psychiatric disorders beyond traditional diagnostic categories, such as autism spectrum disorders, attention-deficit/hyperactivity disorder, schizophrenia, and bipolar disorder. This model is based on the identification of deviations in brain developmental trajectories during critical periods of vulnerability. Using multimodal approaches that integrate clinical, biological, neuroimaging, and neurophysiological data, this framework aims to define an individualized neurodevelopmental burden, opening up new prospects for stratification and the development of personalized treatments tailored to each developmental profile.

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来源期刊
M S-medecine Sciences
M S-medecine Sciences 医学-医学:研究与实验
CiteScore
0.80
自引率
14.30%
发文量
182
审稿时长
4-8 weeks
期刊介绍: m/s offers high-quality review articles in French, covering all areas of biomedical and health research, in a monthly magazine format (10 issues / year). m/s is read by the whole French-speaking community, in France but also in Belgium, Switzerland, Canada, Morocco, Algeria, Tunisia etc. m/s is not a primary publication, and thus will not consider unpublished data. Most articles are invited by the Editors, but spontaneous proposals are welcomed. Each issue combines news and views on the most recent scientific publications, as well as broadly accessible and updated review articles on a specific topic, and essays on science and society, history of science, public health, or reactions to published articles. Each year, m/s also publishes one or two thematic issues focused on a research topic of high interest. All review articles and essays are peer-reviewed.
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