Agatha Ngukuran Jikah , Great Iruoghene Edo , Raghda S. Makia , Emad Yousif , Patrick Othuke Akpoghelie , Tayser Sumer Gaaz , Rapheal Ajiri Opiti , Joseph Oghenewogaga Owheruo , Dina S. Ahmed , Endurance Fegor Isoje , Ufuoma Augustina Igbuku , Arthur Efeoghene Athan Essaghah , Huzaifa Umar
{"title":"维生素A、B1、B2、B3、B12、C、D和E对皮肤健康、免疫和疾病的调节作用","authors":"Agatha Ngukuran Jikah , Great Iruoghene Edo , Raghda S. Makia , Emad Yousif , Patrick Othuke Akpoghelie , Tayser Sumer Gaaz , Rapheal Ajiri Opiti , Joseph Oghenewogaga Owheruo , Dina S. Ahmed , Endurance Fegor Isoje , Ufuoma Augustina Igbuku , Arthur Efeoghene Athan Essaghah , Huzaifa Umar","doi":"10.1016/j.microb.2025.100393","DOIUrl":null,"url":null,"abstract":"<div><div>Numerous skin ailments including acne, atopic dermatitis and psoriasis are a consequence of a compromised skin barrier. Working together with other immune cells of similar functions, the skin is seen as been intricately implicated in innate immunity. This is because several immunological reactions get initiated within the body upon the disruption of the skin barrier. More lately, an increased understanding of skin flora further elucidates the numerous connections linking the immune cells of the body and the skin flora. Vitamins are a very important class of trace elements that exert anti-inflammatory, antimicrobial and antioxidant properties. The development of skin ailments can be impeded by the immunomodulatory activities of vitamins. Exploring the immuno-pharmacology of these trace elements, especially as regards skin diseases may pioneer a new therapeutic trail for the management of skin ailments. This review discusses several micronutrients; vitamins (A, B1, B2, B3, B12, C, D, E) and the roles they play in health, immunity and diseases.</div></div>","PeriodicalId":101246,"journal":{"name":"The Microbe","volume":"7 ","pages":"Article 100393"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The regulatory effects of vitamins A, B1, B2, B3, B12, C, D and E on skin health, immunity and diseases\",\"authors\":\"Agatha Ngukuran Jikah , Great Iruoghene Edo , Raghda S. Makia , Emad Yousif , Patrick Othuke Akpoghelie , Tayser Sumer Gaaz , Rapheal Ajiri Opiti , Joseph Oghenewogaga Owheruo , Dina S. Ahmed , Endurance Fegor Isoje , Ufuoma Augustina Igbuku , Arthur Efeoghene Athan Essaghah , Huzaifa Umar\",\"doi\":\"10.1016/j.microb.2025.100393\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Numerous skin ailments including acne, atopic dermatitis and psoriasis are a consequence of a compromised skin barrier. Working together with other immune cells of similar functions, the skin is seen as been intricately implicated in innate immunity. This is because several immunological reactions get initiated within the body upon the disruption of the skin barrier. More lately, an increased understanding of skin flora further elucidates the numerous connections linking the immune cells of the body and the skin flora. Vitamins are a very important class of trace elements that exert anti-inflammatory, antimicrobial and antioxidant properties. The development of skin ailments can be impeded by the immunomodulatory activities of vitamins. Exploring the immuno-pharmacology of these trace elements, especially as regards skin diseases may pioneer a new therapeutic trail for the management of skin ailments. This review discusses several micronutrients; vitamins (A, B1, B2, B3, B12, C, D, E) and the roles they play in health, immunity and diseases.</div></div>\",\"PeriodicalId\":101246,\"journal\":{\"name\":\"The Microbe\",\"volume\":\"7 \",\"pages\":\"Article 100393\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Microbe\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S295019462500161X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Microbe","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S295019462500161X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The regulatory effects of vitamins A, B1, B2, B3, B12, C, D and E on skin health, immunity and diseases
Numerous skin ailments including acne, atopic dermatitis and psoriasis are a consequence of a compromised skin barrier. Working together with other immune cells of similar functions, the skin is seen as been intricately implicated in innate immunity. This is because several immunological reactions get initiated within the body upon the disruption of the skin barrier. More lately, an increased understanding of skin flora further elucidates the numerous connections linking the immune cells of the body and the skin flora. Vitamins are a very important class of trace elements that exert anti-inflammatory, antimicrobial and antioxidant properties. The development of skin ailments can be impeded by the immunomodulatory activities of vitamins. Exploring the immuno-pharmacology of these trace elements, especially as regards skin diseases may pioneer a new therapeutic trail for the management of skin ailments. This review discusses several micronutrients; vitamins (A, B1, B2, B3, B12, C, D, E) and the roles they play in health, immunity and diseases.
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