7月龄女性真菌性败血症:通过外周血涂片诊断

IF 1.6 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Yihun Bedaso , Tadesse Alemayehu , Amanuel Anegagregn Bizuneh , Dereje Zeleke Haile , Seble Seifu Zeleke , Mekdes Shifeta , Agete Tadewos Hirigo
{"title":"7月龄女性真菌性败血症:通过外周血涂片诊断","authors":"Yihun Bedaso ,&nbsp;Tadesse Alemayehu ,&nbsp;Amanuel Anegagregn Bizuneh ,&nbsp;Dereje Zeleke Haile ,&nbsp;Seble Seifu Zeleke ,&nbsp;Mekdes Shifeta ,&nbsp;Agete Tadewos Hirigo","doi":"10.1016/j.mmcr.2025.100708","DOIUrl":null,"url":null,"abstract":"<div><div>We report a case of a 7-month-old female with prolonged high-grade fever unresponsive to broad-spectrum antibiotics and antimalarial drugs. Despite negative cultures and imaging, a Giemsa-stained peripheral blood smear on day 28 revealed yeast cells, suggesting fungal sepsis in the context of prolonged antibiotic exposure and thrombocytopenia. The patient responded well to oral fluconazole, with full clinical recovery. This case underscores the value of peripheral blood smear examination in diagnosing yeast infections in resource-limited settings.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"48 ","pages":"Article 100708"},"PeriodicalIF":1.6000,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fungal sepsis in a 7-month-old female: diagnosis through peripheral blood smear\",\"authors\":\"Yihun Bedaso ,&nbsp;Tadesse Alemayehu ,&nbsp;Amanuel Anegagregn Bizuneh ,&nbsp;Dereje Zeleke Haile ,&nbsp;Seble Seifu Zeleke ,&nbsp;Mekdes Shifeta ,&nbsp;Agete Tadewos Hirigo\",\"doi\":\"10.1016/j.mmcr.2025.100708\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>We report a case of a 7-month-old female with prolonged high-grade fever unresponsive to broad-spectrum antibiotics and antimalarial drugs. Despite negative cultures and imaging, a Giemsa-stained peripheral blood smear on day 28 revealed yeast cells, suggesting fungal sepsis in the context of prolonged antibiotic exposure and thrombocytopenia. The patient responded well to oral fluconazole, with full clinical recovery. This case underscores the value of peripheral blood smear examination in diagnosing yeast infections in resource-limited settings.</div></div>\",\"PeriodicalId\":51724,\"journal\":{\"name\":\"Medical Mycology Case Reports\",\"volume\":\"48 \",\"pages\":\"Article 100708\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-05-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Mycology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S221175392500017X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S221175392500017X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
引用次数: 0

摘要

我们报告一例7个月大的女性长时间高热对广谱抗生素和抗疟疾药物无反应。尽管阴性培养和成像,第28天的吉姆萨染色外周血涂片显示酵母细胞,提示真菌败血症在长期抗生素暴露和血小板减少的背景下。患者口服氟康唑反应良好,临床完全恢复。本病例强调了外周血涂片检查在资源有限的情况下诊断酵母菌感染的价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fungal sepsis in a 7-month-old female: diagnosis through peripheral blood smear
We report a case of a 7-month-old female with prolonged high-grade fever unresponsive to broad-spectrum antibiotics and antimalarial drugs. Despite negative cultures and imaging, a Giemsa-stained peripheral blood smear on day 28 revealed yeast cells, suggesting fungal sepsis in the context of prolonged antibiotic exposure and thrombocytopenia. The patient responded well to oral fluconazole, with full clinical recovery. This case underscores the value of peripheral blood smear examination in diagnosing yeast infections in resource-limited settings.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Medical Mycology Case Reports
Medical Mycology Case Reports MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
4.00
自引率
0.00%
发文量
48
审稿时长
47 days
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信