{"title":"髋关节置换术后静脉血栓形成的危险因素:荟萃分析。","authors":"Wang Huang, Weiwei Hu, Bangguo Lei, Weichen Huang","doi":"10.1186/s12891-025-08764-z","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Venous thrombosis is a common complication after hip arthroplasty.</p><p><strong>Methods: </strong>PubMed, Embase, the Cochrane Library, and Web of Science were searched for case-control studies on risk factors for venous thrombosis after hip arthroplasty up to September 14, 2023. Data analysis was performed using Stata15.0.</p><p><strong>Results: </strong>This meta-analysis included 15 case-control studies, comprising 17,909 participants, including 1149 patients with venous thrombosis and 16,760 patients without venous thrombosis. The univariate meta-analysis results revealed that age over 70 years old, hypertension, BMI ≥ 25, operation time, stroke, and use of mechanical prophylaxis alone were risk factors for venous thrombosis after hip arthroplasty. Multivariate analysis showed that female, age > 70 years, BMI ≥ 25, cemented prosthesis, and a history of venous thrombosis were the risk factors for venous thrombosis after hip arthroplasty.</p><p><strong>Conclusions: </strong>This study suggests that female sex, age over 70 years, hypertension, a BMI of 25 or higher, duration of operation, stroke, mechanical prevention only, use of a cemented prosthesis, and a history of venous thrombosis are risk factors for venous thrombosis following hip arthroplasty.</p><p><strong>Clinical trial number: </strong>not applicable.</p>","PeriodicalId":9189,"journal":{"name":"BMC Musculoskeletal Disorders","volume":"26 1","pages":"508"},"PeriodicalIF":2.2000,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12100892/pdf/","citationCount":"0","resultStr":"{\"title\":\"Risk factors for venous thrombosis after hip arthroplasty: a meta-analysis.\",\"authors\":\"Wang Huang, Weiwei Hu, Bangguo Lei, Weichen Huang\",\"doi\":\"10.1186/s12891-025-08764-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Venous thrombosis is a common complication after hip arthroplasty.</p><p><strong>Methods: </strong>PubMed, Embase, the Cochrane Library, and Web of Science were searched for case-control studies on risk factors for venous thrombosis after hip arthroplasty up to September 14, 2023. Data analysis was performed using Stata15.0.</p><p><strong>Results: </strong>This meta-analysis included 15 case-control studies, comprising 17,909 participants, including 1149 patients with venous thrombosis and 16,760 patients without venous thrombosis. The univariate meta-analysis results revealed that age over 70 years old, hypertension, BMI ≥ 25, operation time, stroke, and use of mechanical prophylaxis alone were risk factors for venous thrombosis after hip arthroplasty. Multivariate analysis showed that female, age > 70 years, BMI ≥ 25, cemented prosthesis, and a history of venous thrombosis were the risk factors for venous thrombosis after hip arthroplasty.</p><p><strong>Conclusions: </strong>This study suggests that female sex, age over 70 years, hypertension, a BMI of 25 or higher, duration of operation, stroke, mechanical prevention only, use of a cemented prosthesis, and a history of venous thrombosis are risk factors for venous thrombosis following hip arthroplasty.</p><p><strong>Clinical trial number: </strong>not applicable.</p>\",\"PeriodicalId\":9189,\"journal\":{\"name\":\"BMC Musculoskeletal Disorders\",\"volume\":\"26 1\",\"pages\":\"508\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-05-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12100892/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Musculoskeletal Disorders\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12891-025-08764-z\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ORTHOPEDICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Musculoskeletal Disorders","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12891-025-08764-z","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ORTHOPEDICS","Score":null,"Total":0}
引用次数: 0
摘要
背景:静脉血栓形成是髋关节置换术后常见的并发症。方法:检索PubMed、Embase、Cochrane图书馆和Web of Science,检索截至2023年9月14日有关髋关节置换术后静脉血栓形成危险因素的病例对照研究。使用Stata15.0进行数据分析。结果:本荟萃分析纳入15项病例对照研究,包括17909名参与者,其中1149名静脉血栓患者和16760名无静脉血栓患者。单因素荟萃分析结果显示,年龄超过70岁、高血压、BMI≥25、手术时间、卒中和单独使用机械预防是髋关节置换术后静脉血栓形成的危险因素。多因素分析显示,女性、年龄bb0 ~ 70岁、BMI≥25、假体骨水泥、有静脉血栓形成史是髋关节置换术后静脉血栓形成的危险因素。结论:本研究提示,女性、年龄超过70岁、高血压、BMI≥25、手术时间、卒中、单纯机械预防、使用骨水泥假体以及有静脉血栓形成史是髋关节置换术后静脉血栓形成的危险因素。临床试验号:不适用。
Risk factors for venous thrombosis after hip arthroplasty: a meta-analysis.
Background: Venous thrombosis is a common complication after hip arthroplasty.
Methods: PubMed, Embase, the Cochrane Library, and Web of Science were searched for case-control studies on risk factors for venous thrombosis after hip arthroplasty up to September 14, 2023. Data analysis was performed using Stata15.0.
Results: This meta-analysis included 15 case-control studies, comprising 17,909 participants, including 1149 patients with venous thrombosis and 16,760 patients without venous thrombosis. The univariate meta-analysis results revealed that age over 70 years old, hypertension, BMI ≥ 25, operation time, stroke, and use of mechanical prophylaxis alone were risk factors for venous thrombosis after hip arthroplasty. Multivariate analysis showed that female, age > 70 years, BMI ≥ 25, cemented prosthesis, and a history of venous thrombosis were the risk factors for venous thrombosis after hip arthroplasty.
Conclusions: This study suggests that female sex, age over 70 years, hypertension, a BMI of 25 or higher, duration of operation, stroke, mechanical prevention only, use of a cemented prosthesis, and a history of venous thrombosis are risk factors for venous thrombosis following hip arthroplasty.
期刊介绍:
BMC Musculoskeletal Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of musculoskeletal disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
The scope of the Journal covers research into rheumatic diseases where the primary focus relates specifically to a component(s) of the musculoskeletal system.