多发1型内分泌肿瘤并发恶性胰岛素瘤复发1例。

IF 0.4 Q4 SURGERY
Journal of Surgical Case Reports Pub Date : 2025-05-22 eCollection Date: 2025-05-01 DOI:10.1093/jscr/rjaf335
Marcela Palomo, Ximena Rivera, Isabella Santamarina
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引用次数: 0

摘要

胰岛素瘤是一种罕见的胰腺神经内分泌肿瘤,通常是良性的,但在多发性1型内分泌瘤(MEN1)的背景下,它们可能是恶性的和复发的。本病例报告介绍了一名患有MEN1的58岁男性,他最初于2019年因胰腺尾部的恶性胰岛素瘤接受了部分胰腺切除术。尽管2021年复发,但患者拒绝手术;然而,在2025年,他表现为低血糖,影像学显示胰腺头部有一个3厘米的肿块。他接受了惠普尔手术,组织病理学分析证实了复发性胰岛素瘤。该病例强调了MEN1恶性胰岛素瘤治疗的临床挑战,强调了长期随访和分阶段手术干预的重要性,因为复发的风险很高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recurrence of malignant insulinoma in the context of multiple endocrine neoplasia type 1: a case report.

Insulinomas are rare pancreatic neuroendocrine tumors, typically benign, but in the context of multiple endocrine neoplasia type 1 (MEN1), they can be malignant and recurrent. This case report presents a 58-year-old man with MEN1 who initially underwent partial pancreatectomy for a malignant insulinoma in the pancreatic tail in 2019. Despite recurrence in 2021, the patient declined surgery; however, in 2025, he presented with hypoglycemia and imaging revealed a 3-cm mass in the pancreatic head. He underwent a Whipple procedure, with histopathological analysis confirming the recurrent insulinoma. This case highlights the clinical challenge of managing malignant insulinomas in MEN1, emphasizing the importance of long-term follow-up and staged surgical interventions due to the high risk of recurrence.

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CiteScore
0.70
自引率
0.00%
发文量
559
审稿时长
11 weeks
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