{"title":"根植于调控:作为浦肯野细胞树突乔木园丁的microrna。","authors":"Cheryl Brandenburg, Roy V Sillitoe","doi":"10.1016/j.neuron.2025.04.016","DOIUrl":null,"url":null,"abstract":"<p><p>Zolboot et al.<sup>1</sup> developed tools to manipulate and map microRNA function in cerebellar Purkinje cells with temporal precision, revealing key roles in dendritic development and circuit connectivity. Their approach provides insight into microRNA-mediated regulation of neurodevelopment in sparse neuronal populations.</p>","PeriodicalId":19313,"journal":{"name":"Neuron","volume":"113 10","pages":"1463-1465"},"PeriodicalIF":15.0000,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rooted in regulation: MicroRNAs as gardeners of the Purkinje cell dendritic arbor.\",\"authors\":\"Cheryl Brandenburg, Roy V Sillitoe\",\"doi\":\"10.1016/j.neuron.2025.04.016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Zolboot et al.<sup>1</sup> developed tools to manipulate and map microRNA function in cerebellar Purkinje cells with temporal precision, revealing key roles in dendritic development and circuit connectivity. Their approach provides insight into microRNA-mediated regulation of neurodevelopment in sparse neuronal populations.</p>\",\"PeriodicalId\":19313,\"journal\":{\"name\":\"Neuron\",\"volume\":\"113 10\",\"pages\":\"1463-1465\"},\"PeriodicalIF\":15.0000,\"publicationDate\":\"2025-05-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neuron\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.neuron.2025.04.016\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuron","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.neuron.2025.04.016","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
Rooted in regulation: MicroRNAs as gardeners of the Purkinje cell dendritic arbor.
Zolboot et al.1 developed tools to manipulate and map microRNA function in cerebellar Purkinje cells with temporal precision, revealing key roles in dendritic development and circuit connectivity. Their approach provides insight into microRNA-mediated regulation of neurodevelopment in sparse neuronal populations.
期刊介绍:
Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.